INTRODUCTION Gut hypoperfusion frequently occurs in clinical settings such as shock, aortic surgery and other major operations . Marked reduction of gut blood flow even during colon cancer resection, a relatively minor insult as compared to esophageal and hepato-biliary-pancreatic surgeries, has been demonstrated . Gut ischemia reperfusion(I/R) causes not only gut morphological changes but also...

SUMMARY Carcinoma of the liver with invasion and metastases has been observed in rats fed diets containing 0.1 or 0.06 percent m toluylenediamine. Histologically all the tumors were hepato cellular carcinomas closely resembling those following the administration of other hepatic chemical carcinogens. The simultaneous administration of DL-ethionine had a synergistic effect with m-toluylenediamin...

AIM The aims of this study were to compare ultrasound fetoplacental parameters and to calculate Hepato-Cephalic Index (HCI) as a new predictor of IUGR. METHODS AND MATERIAL A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=6...

Objective: The present study was carried out to evaluate the adverse effects of cefotaxime at two different doses on some biochemical parameters in albino rats. Histopathological changes in liver and kidney induced by cefotaxime were also investigated. Methods: Thirty rats were randomly divided into 3 equal groups; the first group was received distilled water and kept as a control. The second g...

AIM To determine the effects of high osmolarity contrast media (HOCM) and iso-osmolar contrast media (CM) application, with or without pressure, on hepato-pancreato-biliary (HPB) system. METHODS Sixty rats were divided into six equal groups as follows: Group 1: (0.9% NaCl, control), Group 2: (diatrizoate meglumine Na, ionic HOCM, Urographin), Group 3: (iodixanol, iso-osmolar non-ionic CM, Vis...

In 1933, John McMichael was awarded a gold medal by the University of Edinburgh for his M.D. thesis. This was entitled 'The pathology of hepatolienal fibrosis' and was published in an abridged form in 1934 in the Journal of Pathology and Bacteriology. It was a masterly account of the pathological changes associated with portal hypertension. Pathological changes in spleen and portal vasculature ...

WARNINGS: LIFE THREATENING ADVERSE REACTIONS See full prescribing information for complete boxed warning. Hepato toxicity, including fatalities, usually during first 6 months o f treatment. Children under the age of two years and patients with mitochondrial disorders are at higher risk. Monitor patients c losely, and perform serum liver testing prior to therapy and at frequent intervals thereaf...

To the Editor: Knowledge has evolved and the use of staplers in gastrointestinal surgery is now widespread. They are associated with low rates of postoperative complications. Postoperative anastomotic complications with stapling devices are relatively rare, with a reported incidence between 0 and 2.5%.1 How to cite this article: Krishnan A, Velayutham V, Satyanesan J. Endoscopic Management of P...

Although prostate cancer is common in the western world and is associated with favorable overall survival, neuroendocrine prostate cancer is difficult to detect and is known to aggressively metastasize throughout the body. This subset of disease thus has a poor prognosis, and early detection and treatment of neuroendocrine prostate cancer may increase overall survival. We present a case of a no...

Monocrotophos administration at intervals induced variable responses in phosphatases, transaminases and aldolase of liver and plasma. Hepato-toxicity was aggravated under protein deficient state. A weak resistance to toxicity was observed in rats on low protein diet (5%). However, animals fed on protein enriched diet (20%) indicated an elevation in tissue defense mechanism and were able to comb...