A stratified age matched sample of 564 general hospital nurses, assistant nurses, and porters was studied for antibody to hepatitis A virus (anti-HAV), hepatitis B surface antigen (HBsAg), and antibody to hepatitis B surface antigen (anti-HBs), and these data were compared with serum aspartate aminotransferase (AST) and identified episodes of hepatitis. The overall prevalence of anti-HBs was in...

Warm antibody autoimmune haemolytic anaemia, a rare disease (0.2-1 per 100,000 populations), is due to the presence of warm agglutinins that react with protein antigens on the surface of red blood cells causing their premature destruction. Here, we present a case report of a 10 year old girl who came with features of haemolytic anaemia and history of blood transfusion since 3 years. On admissio...

Key words: fibrosing cholestatic hepatitis; graft failure; surface antigen, as well as anti-HBc and anti-HBe hepatitis B virus; interferon-a; renal transplantation antibodies. He was seronegative for HBeAg, anti-HCV antibody (ELISA 2) and cytomegalovirus (CMV). Serum hepatitis B virus DNA determined by PCR was negative. His pretransplant liver function was normal.

OBJECTIVE To evaluate viral vaccine antibody levels in children with acute lymphoblastic leukemia after chemotherapy and after vaccine booster doses. METHODS Antibody levels against hepatitis B, rubella, measles and mumps vaccine antigens were evaluated in 33 children after completing chemotherapy (before and after vaccine booster doses) and the results were compared to the data of 33 healthy...

Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the p...

The ability of human semen and saliva to transmit hepatitis B virus (HBV) by parenteral and nonparenteral routes was studied. Semen, donated by a hepatitis B surface antigen (HBsAg)- and hepatitis B e antigen (HBeAg)-positive carrier, was administered to one gibbon by subcutaneous inoculation and to another by intravaginal instillation. Both developed HBsAg, followed by the development of antib...

800x600 background : hepatitis b and c infections have remained major global health burdens during the most recent century. the viral agents responsible for these diseases share common modes of transmission with human immunodeficiency virus (hiv) such as needle-sharing in iv drug abusers. coinfection of hepatitis b or c with hiv increases the rate of progression of chronic liver disease. given ...

Replication of the hepatitis B virus is suppressed by deficiency of the X protein. Although several molecules that block cellular targets of X protein reduce the production of hepatitis B virus progeny, the effect of a specific inhibitor of X protein on viral replication has not been investigated. To block X protein specifically, we adopted an intracellular expression approach using H7 single c...

We developed an immunogen to stimulate multivalent immunity against hepatitis B surface antigen (HBsAg) and hepatitis B core antigens (HBcAg). Immune responses specific for both HBsAg and HBcAg play an important role in controlling the infection. HBsAg-specific antibodies mediate elimination of virions at an early stage of infection and prevent the spread of virus. The immunogen was constructed...

Introduction Hepatitis B virus (HBV) and hepatitis C virus (HCV) are hepatotropic viruses of public health significance worldwide. Despite their severe clinical impact in HIV-infected patients, there is inadequate information regarding the epidemiology of hepatitis/HIV coinfections in Ethiopia. Thus, this study aimed to determine the prevalence of HBV and HCV infections among HIV-infected patie...