The low perioperative morbidity and shorter hospital stay associated with laparoscopic hepatectomy have made it an often-used option at many liver centers, despite the fact that many patients with hepatocellular carcinoma have cirrhosis, which makes the procedure more difficult and dangerous. Type of surgical procedure proves not to be a primary risk factor for poor outcomes after hepatic resec...

Role of hepatic transporters in prevention of bile-acid toxicity 1 after partial hepatectomy in mice 2 3 4 5 6 7 8 Iván L. Csanaky, Lauren M. Aleksunes, Yuji Tanaka, and Curtis D. Klaassen 9 10 11 12 13 14 15 16 Department of Pharmacology, Toxicology, and Therapeutics 17 University of Kansas Medical Center 18 3901 Rainbow Blvd. 19 Kansas City, Kansas 20 21 22 23 Running head: Bile acids and hep...

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) could induce extensive and rapid future liver remnant hypertrophy. However, the morbidity for ALPPS is very high. This paper reports a modified ALPPS (associating microwave ablation and portal vein ligation for staged hepatectomy, AMAPS), which was successfully applied in the treatment of huge hepatocellular car...

There are a total of five structures that have to be reconstructed in DDLT. These include the suprahepatic and infrahepatic vena cava, the portal vein, the hepatic artery and the bile duct. Prior to describing the various methods of implantation of the donor liver, we will briefly review the different options available for the recipient hepatectomy, as the surgeon’s choice of reconstruction of ...

with open hepatectomy. The indications for LH have gradually expanded, from local resection of benign neoplasms at the liver edge to hemihepatectomy and more extensive anatomical resections, segmentectomy for malignant neoplasms, and donor hepatectomy for liver transplantations. The numbers of LH procedures performed are increasing exponentially in surgical centers worldwide [1,2]. In some high...

Anatomic distortion and displacement of hilar structures due to liver lobe atrophy and hypertrophy occasionally complicates the surgical approach for biliary stricture repair. Benign biliary stricture following hepatic resection deserves special consideration in this regard because the inevitable hypertrophy of the residual liver causes marked rotation and displacement of the hepatic hilum that...

In this era of combination chemotherapy and biologic treatment, the ability to downsize tumors that were previously unresectable will increase the need for major hepatic resections. This makes teaching consistent surgical approaches to these difficult cases imperative. Herein we outline a standardized surgical approach to right hepatectomy, which allows the procedure to be divided into a series...

HEADINGS Aged. Hepatectomy. Postoperative complications. Morbidity. Mortality. ABSTRACT Introduction Life expectancy of the population has increased in recent years as a result of human development, leading to an increase in the incidence of primary and secondary neoplasms of the liver. Medicine has been following this process, but there is still fear of aggressive surgical treatment in elderly...

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a recently introduced technique aimed to perform two-stage hepatectomy in patients with a variety of primary or secondary neoplastic lesions. ALPSS is based on a preliminary liver resection associated with ligation of the portal branch directed to the diseased hemiliver (DH), followed by hepatectomy after an ...

In male rats, hepatic glyoxalase activity and reduced glutathione, the cofactor for this enzyme system, approximately double 12 hr after partial (2/3) or sham hepatectomy, in which the liver lobes were handled during the sham operation. These changes precede by 10 to 12 hr the anticipated DNA synthesis after partial hepatectomy and by about 24 hr the smaller, but prolonged, DNA synthesis that o...