BACKGROUND AND OBJECTIVES Since atracurium can cause hypotension in humans, the hemodynamic effects of atracurium and cisatracurium as well as the hemodynamic protection of diphenhydramine and cimetidine were investigated in rats. METHODS 1) Wistar rats were anesthetized with sodium pentobarbital and prepared according to Brown et al. to evaluate different doses of atracurium and cisatracuriu...

OBJECTIVES We investigated endocrine correlates of the hemodynamic changes induced by carbon dioxide pneumoperitoneum (PNO). We then studied whether clonidine might modulate the hemodynamic changes induced by PNO by reducing release of catecholamines and vasopressin. BACKGROUND Both mechanical and neurohumoral factors contribute to the hemodynamic changes induced by carbon dioxide PNO. Severa...

BACKGROUND AND OBJECTIVES Isoflurane is considered a safe inhalational anesthetic. It has a low level of biotransformation, and low hepatic and renal toxicity. In clinical concentrations, it has minimal negative inotropic effect, causes a small reduction in systemic vascular resistance, and, rarely, can cause cardiac arrhythmias. The objective of this report was to present a case of severe hemo...

The success of propranolol in treating the symptoms of angina pectoris has raised questions about the effects of beta-adrenergic blockade on the hemodynamic functions, myocardial mechanics, energetics, and metabolic functions. Five milligrams of propranolol was given intravenously to 27 human subjects, 18 with and nine without angiographically proven coronary atherosclerosis. The drug produced ...

The patient had complete placenta previa and a giant placental tumor, and had a history of repair for cor triatriatum (CorT) 19 years previously. After anesthetic induction with remifentanil, thiamylal, and rocuronium, tachyarrhythmia occurred following multifocal ventricular premature contraction. Treatment with lidocaine was not effective. However, tachyarrhythmia converted naturally after de...

BACKGROUND Cardiac hypertrophy is a fundamental adaptive response to hemodynamic overload; how mechanical load induces cardiac hypertrophy, however, remains elusive. It was recently reported that activation of a calcium-dependent phosphatase, calcineurin, induces cardiac hypertrophy. In the present study, we examined whether calcineurin plays a critical role in pressure overload-induced cardiac...

Intralipid (20 percent, 500 ml) was infused fast (5 h) or slow (10 h) randomly in patients with lung injury to relate changes in plasma prostaglandin (PG) concentrations to gas exchange and pulmonary hemodynamics. Data were collected at baseline, midpoint of infusion, and 2 h following infusion. Vasodilator and vasoconstrictor PG metabolites, 6-keto-PGF1 alpha, and thromboxane B2, respectively,...

In this study, we characterized cerebral blood flow changes by assessment of blood flow parameters in neck arteries using carotid duplex ultrasonography and predictive factors for these hemodynamic changes. Hemodynamic variables were measured before and during hemodialysis in 81 patients with an arteriovenous access in their arm. Hemodialysis produced significant lowering in peak systolic veloc...

The purpose of this paper was to investigate the hemodynamic parameters associated with the blood flow in failed coronary venous bypass grafts using a computational fluid dynamics (CFD) technique. A narrowed section creates bypass graft constriction and disturbed flow. This change of the flow direction alters significantly the local hemodynamic parameters. In this paper, a patient specific thre...

Spontaneous bilateral cerebellar infarction in the territory of the superior cerebellar arteries is extremely rare. Occasionally there have been reports of bilateral cerebellar infarction due to vertebrobasilar atherosclerotic occlusion or stenosis, whereas no report of bilateral cerebellar infarction due to complicated hemodynamic changes. In this report, we present a patient with bilateral ce...