WHO During the past decade there have been major efforts to plan, implement, and sustain measures for reducing the burden of human disease that accompanies helminth infections. Further impetus was provided at the Fifty-fourth World Health Assembly, when WHO Member States were urged to ensure access to essential anthelminthic drugs in health services located where the parasites – schistosomes, r...

It has been shown that the presence of certain helminth infections in humans, including schistosomes, may reduce the propensity to develop allergies in infected populations. Using a mouse model of schistosome worm vs worm + egg infection, our objective was to dissect the mechanisms underlying the inverse relationship between helminth infections and allergies. We have demonstrated that conventio...

More than one-third of the world's population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease. The severity of the disease is strongly related to parasite density and the host's immune responses. Furthermore, coi...

BACKGROUND Helminth infections are known to modulate innate and adaptive immune responses in active and latent tuberculosis (TB). However, the role of helminth infections in modulating responses associated with inflammation and immune activation (reflecting disease activity and/or severity) in TB is not known. METHODOLOGY We measured markers of inflammation and immune activation in active pul...

OBJECTIVE To describe the patterns of single and multiple helminth infection in school children from Busia District, Kenya. DESIGN A cross-sectional school survey using a randomly selected sample, forming part of an evaluation study of an ongoing deworming project. SETTING Budalangi and Funyula divisions of Busia District, Western Province, Kenya. SUBJECTS One thousand seven hundred and t...

Aim: Soiltransmitted helminths (STH) and schistosomiasis are a major public health problem in Kenya as well as in many other tropical countries. Intestinal parasite infections have been associated with malabsorption and nutrient loses that can lead to malnutrition. Malnutrition is considered one of the most prevalent conditions among children in rural population. The aim of this study was to in...

background: wild boars, sus scrofa , of wide distribution considered as a potential source of zoonotic parasites. the current study aimed to assess the prevalence of helminth infections in wild boars in the persian gulf coastal area (bushehr province), southwestern iran. methods: twenty-five wild boars, including 11 males and 14 females, were collected during a course of vertebrate pest control...

Parasitic roundworms and flatworms, defined broadly as helminths, are estimated to infect over 1 billion people worldwide, and are particularly prevalent in developing, resource-strained communities. The consequences of these infections are immense and wide reaching, resulting in massive reductions in local and global economic productivity and contributing to millions of deaths per year. Helmin...

Background Rodents are considered as reservoirs of various zoonotic diseases including helminthic infections. The current study aimed to evaluate the prevalence of helminth infections in rodents, in Boyer-Ahmad district, Southwestern Iran. Methods Overall, 52 rodents were captured from various areas of the district by Sherman live traps. The animals were then euthanized and dissected. During ...

BACKGROUND Approximately one-third of the world population is infected with M. tuberculosis and helminths (Kariminia et al. (2009), Walson et al. (2010)). Pregnancy and Helminth infection are known to suppress the TH1 response (Kariminia et al. (2009), Elias et al. (2006)) on which the QuantiFERON Gold in Tube (QFT-GIT) assay, that measures the released IFN-γ upon in vitro stimulation with myco...