OBJECTIVE To determine the etiology and site of leak of cerebrospinal fluid (CSF) rhinorrhea and the surgical efficacy of Functional Endoscopic Sinus Surgery (FESS), in closing the defect of CSF leak by different graft materials. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY Department of ENT-Head and Neck Surgery, Dow University of Health Sciences, Karachi, from September 2005 to D...

OBJECTIVE • To determine if the RENAL nephrometry score is associated with urine leak after partial nephrectomy for tumours ≤ 7 cm. PATIENTS AND METHODS • Thirty-one patients who developed urine leak after partial nephrectomy between 1998 and 2006 were identified. Each patient was individually matched (1 : 4 by age, gender and surgery date) to 124 patients who had undergone partial nephrectom...

Abstract A multi-layer welded bellows made of 00Cr17Ni14Mo2 was found to have leakage points in the heat-affected zone weld during airtight inspection and leak detection by helium mass spectrometry. In view multilayer bellows, reasons for areanalyzed means macroscopic observation, electron microscope energy spectrum analysis, metallographic examination, microhardness test chemical composition a...

Maintenance of vascular integrity is critical for homeostasis, and temporally and spatially regulated vascular leak is a central feature of inflammation. Sphingosine-1-phosphate (S1P) can regulate endothelial barrier function, but the sources of the S1P that provide this activity in vivo and its importance in modulating different inflammatory responses are unknown. We report here that mutant mi...

Excessive calcium influx is important in the irreversible injury of cardiac myocytes and other cell types. The mechanism is unknown, but possibilities include L-type channels, Na(+)-Ca2+ exchange, sarcolemmal (SL) defects, and calcium leak channels. In this study, metabolic inhibition was used to induce ATP depletion and augmented calcium influx in cultured cardiac myocytes. Inhibition of the L...

A growing body of evidence suggests that mitochondrial proton-leak functions as a regulator of reactive oxygen species production and its modulation may limit oxidative injury to tissues. The main purpose of this work was to characterize the proton-leak of brain cortical mitochondria from long-term hyperglycemic and insulin-induced recurrent hypoglycemic rats through the modulation of the uncou...

Leak localization is essential for the safety and maintenance of storage vessels. This study proposes a novel circular acoustic emission sensor array to realize the continuous CO₂ leak localization from a circular hole on the surface of a large storage vessel in a carbon capture and storage system. Advantages of the proposed array are analyzed and compared with the common sparse arrays. Experim...

Pneumothorax is a relatively common condition that is usually managed either conservatively, by chest tube drainage or, if a refractory air leak persists, then with cardiothoracic intervention. However, there is a small group of patients with a persistent air leak in whom surgical intervention is felt to be inappropriate. This study looks at a novel management strategy in a patient presenting w...

risk assessment and management of petrochemical feed and product transportation pipelines is very important to preventing probable accidents. so, 60 pipelines evaluated by chemical exposure index and chlorine pipeline due to high hazard distances selected for relative risk analysis. the chlorine pipeline with 3468 meter length divided to 100 meter sections, and third party damage index (tpdi), ...

Post-extubation stridor and upper-airway obstruction are multifactorial in etiology and can occur as a result of laryngotracheal edema, intubation trauma, excessive cuff pressure with mucosal ulceration, and prolonged intubation with secondary inflammation and granuloma formation.1 Cuff leak tests (CLTs) were introduced in an attempt to predict post-extubation upper-airway obstruction and reduc...