نتایج جستجو برای: hdm 4
تعداد نتایج: 1304326 فیلتر نتایج به سال:
Big Data applications are becoming more complex and experiencing frequent changes and updates. In practice, manual optimization of complex big data jobs is time-consuming and error-prone. Maintenance and management of evolving big data applications is a challenging task as well. We demonstrate HDM, Hierarchically Distributed Data Matrix, as a big data processing framework with built-in data flo...
As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House dust mite (HDM) allergy is very common. The aim of the current experience was to describe the clinical profile of HDM-allergic patients with AR who received AIT in a real world model, such ...
Abstract Background House dust mites (HDM) are considered as a major source of indoor aeroallergen all over the world that precipitate allergic reactions including rhinoconjunctivitis, food allergy, atopic dermatitis, and asthma. In this study, we aimed to assess clinical laboratory profile some Egyptian asthmatic children who sensitized house determine association HDM sensitization severity as...
Der p 23, a new, major house dust mite (HDM) allergen that is recognized by >70% of HDM-allergic patients, has high allergenic activity and, therefore, must be considered an important component for HDM-specific immunotherapy. We constructed and characterized a hypoallergenic Der p 23 vaccine for HDM immunotherapy. Three nonallergenic peptides from the C-terminal IgE epitope-containing part of D...
Levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, are increased in lung, sputum, exhaled breath condensate and plasma samples from asthma patients. ADMA is metabolized primarily by dimethylarginine dimethylaminohydrolase 1 (DDAH1) and DDAH2. We determined the effect of DDAH1 overexpression on development of allergic inflammation in a mouse model of ...
β-(1,3)-Glucan is present in mould cell walls and frequently detected in house dust mite (HDM) faeces. β-Glucan exposure is thought to be associated with pulmonary allergic inflammation in mouse and man, although the published data are inconsistent. Here, we show that highly purified β-glucan exacerbates HDM-induced eosinophilic, T helper 2 type airway responses by acting as an adjuvant, promot...
This paper presents a new parameter estimation algorithm based on the Extended Kalman Filter (EKF) for the recently proposed statistical coarticulatory Hidden Dynamic Model (HDM). We show how the EKF parameter estimation algorithm unifies and simplifies the estimation of both the state and parameter vectors. Experiments based on N-best rescoring demonstrate superior performance of the (contexti...
UNLABELLED Aims/Introduction: The combination of hypertension with diabetes mellitus (DM) has been recognized as a critical risk factor for cardiovascular disease (CVD). We investigated the blood pressure levels in hypertensive patients with DM (HDM patients) compared with those without DM (HnDM patients). Furthermore, we examined the effect of risk factors, including chronic kidney disease (C...
BACKGROUND Southeast Asian populations are increasingly affected by allergic airway diseases. Etiology and specific causes, however, are still unknown. The aim of this study is therefore to identify allergens and risk factors for the high prevalence of allergic airway disease in the tropical urban environment. METHODS Symptoms of allergic rhinitis (AR), asthma, and allergic dermatitis were re...
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