Resumen. Ante la necesidad de gestionar la información que manejan, las organizaciones disponen de dos tipos de herramientas informáticas ampliamente utilizadas: los sistemas de información basados en bases de datos (SIBD) que resultan costosos de desarrollar y son poco flexibles; y las hojas de cálculo (HdC), que ponen en peligro la integridad de los datos y son limitadas en cuanto a la explot...

BackgroundHigh-dose chemotherapy with autologous stem cell rescue (HDC-ASCR) is the most effective treatment in transplant-eligible patients multiple myeloma (MM). The complication rate of the...

Prinz, Christian, Robert Zanner, Markus Gerhard, Sabine Mahr, Nina Neumayer, Barbara Höhne-Zell, and Manfred Gratzl. The mechanism of histamine secretion from gastric enterochromaffin-like cells. Am. J. Physiol. 277 (Cell Physiol. 46): C845–C855, 1999.— Enterochromaffin-like (ECL) cells play a pivotal role in the peripheral regulation of gastric acid secretion as they respond to the functionall...

At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a self-renewal factor, Unpaired (Upd), that activates the JAK-STAT pathway in adjacent stem cells to regulate stem cell behavior. Therefore, apical hub cells are a critical component of the stem cell niche in the testis. In the course of a screen to i...

The dynamic magnetostriction characteristics of an Fe-based nanocrystalline FeCuNbSiB alloy are investigated as a function of the dc bias magnetic field. The experimental results show that the piezomagnetic coefficient of FeCuNbSiB is about 2.1 times higher than that of Terfenol-D at the low dc magnetic bias Hdc = 46 Oe. Moreover, FeCuNbSiB has a large resonant dynamic strain coefficient at qui...

The use of molecular tools for early and rapid detection of gram-negative histamine-producing bacteria is important for preventing the accumulation of histamine in fish products. To date, no molecular detection or identification system for gram-negative histamine-producing bacteria has been developed. A molecular method that allows the rapid detection of gram-negative histamine producers by PCR...

OBJECTIVE To examine the influence of high-dose chemotherapy (HDC) and autologous stem cell transplantation (ASCT) on joint damage in patients with rheumatoid arthritis. METHODS Eight patients with active, refractory, progressively erosive RA were treated. The conditioning regimen consisted of intravenous administration of high doses of cyclophosphamide (totaling 200 mg/kg), with subsequent r...

Glucocorticoids (GCs) are frequently used for treating and preventing chronic lung disease and circulatory dysfunction in premature infants. However, there is growing concern about the detrimental effects of systemic GC administration on neurodevelopment. The first choice of GCs to minimize the adverse effects on the developing brain is still under debate. We investigated the effect of commonly...

Eight patients with stage III aggressive multiple myeloma, refractory to current chemotherapy in six cases, were treated by high-dose chemotherapy (nitrosourea, etoposide, and melphalan) (HDC) and total body irradiation (TBI), followed by autografting with blood stem cells. These cells were previously collected by leukapheresis performed during hematologic recovery following cytotoxic drug-indu...

Collaborative spectrum sensing has attracted significant research attention in the last few years and is widely accepted as a viable approach to improve spectrum sensing reliability. Fusing data from multiple opportunistic users (OUs) in order to produce reliable sensing results implies a reliance on the OU to provide correct information. In the presence of malfunctioning or selfish users, perf...