Hemoglobin A2 (Hb A2) and hemoglobin F (Hb F) are important analytes in the diagnosis and follow up of Hb diseases. We evaluated a new capillary zone electrophoresis (CZE) kit for Hb A2 and Hb F measurements. The imprecision ranged from 3% to 6% for Hb A2 and Hb F at physiological and pathological concentrations. The method compared well with cation-exchange HPLC for Hb A2 and Hb F and with ani...

BACKGROUND We sought to identify the frequency and mechanisms of anemia after bariatric surgery in a bariatric surgery program at the Medical College of Wisconsin, (Milwaukee, WI). Anemia after bariatric surgery has often been attributed to iron deficiency, although an inflammatory component might be present, making the anemia after surgery mechanistically complex. METHODS The body mass index...

conclusions in type ii diabetes, the increased susceptibility of ldl to oxidation is related to hyperglycemia and low aop. background type ii diabetes mellitus is a complex heterogeneous group of metabolic conditions characterized by an increased level of blood glucose, due to impairment in insulin action and/or insulin secretion. hyperglycemia is a major factor in the pathogenesis of atheroscl...

Background: Hemoglobin (Hb) and hematocrit (Hct) have been used routinely in the diagnosis of neonatal anemia and polycythemia. Objective: To measure the cord blood Hb and Hct and to determine their association with maternal Hb and Hct. Methods: 170 healthy neonates born through normal vaginal delivery with gestation age of 37-42 wks and birth weight of 2.5-4 kg, and their mothers were included...

Takeuchi, Kazuhiko, Noriyuki Miyata, Marija Renic, David R. Harder, and Richard J. Roman. Hemoglobin, NO, and 20-HETE interactions in mediating cerebral vasoconstriction following SAH. Am J Physiol Regul Integr Comp Physiol 290: R84–R89, 2006. First published September 15, 2005; doi:10.1152/ajpregu.00445.2005.—Recent studies have indicated that 20-hydroxyeicosatetraenoic acid (20-HETE) contribu...

We present the results of Monte Carlo mass-loss computations for hot low-mass stars, specifically for Subdwarf B (SdB) stars. It is shown that the massloss rates on the Horizontal Branch (HB) computed from radiative line-driven wind models are not high enough to create SdB stars. We argue, however, that mass loss plays a role in the chemical abundance patterns observed both in field SdB stars, ...

AIM To determine the variation of hemoglobin (Hb) in two groups of miners working at different altitudes. METHODOLOGY A longitudinal study conducted in a private company. Hb was obtained from entrance exams and annual checks of workers at two locations: at sea level and at Peruvian highlands (4,100 m), taken by trained staff and equipment calibrated to environmental conditions. We analyzed va...

Objective. To determine changes in hemoglobin concentration at second measurements after a normal hemoglobin concentration was detected at first booking during pregnancy at low and at high altitudes. Methods. This is a secondary analysis of a large database obtained from the Perinatal Information System in Peru which includes 379,816 pregnant women and their babies from 43 maternity units in Pe...

To test the hypothesis that the human red blood cell aging process participates actively in the adaptation to hypoxia, we studied some physical and biochemical hematologic variables in 10 volunteers at sea level (SL) and after 1 (1WK) or 5 wk (5WK) of exposure to 5,050-m altitude. The 2,3-diphosphoglycerate-to-hemoglobin ratio (2,3-DPG/Hb) was 0.88 +/- 0.03 (mol/mol) at SL and increased to 1.08...