Inappropriate expression of 3-methyladenine (3MeA) DNA glycosylases has been shown to have harmful effects on microbial and mammalian cells. To understand the underlying reasons for this phenomenon, we have determined how DNA glycosylase activity and substrate specificity modulate glycosylase effects in Escherichia coli. We compared the effects of two 3MeA DNA glycosylases with very different s...

This work uses anonymized geolocation data from 60 million mobile phone users in Brazil to quantify the impact of coronavirus lockdown measures on social distancing. The results confirm that current share population staying home is lower than target set by public authorities combat spread COVID-19. Using difference-in-difference and panel regression evaluate determinants distancing, this paper ...