Background: Cystic echinococcosis (CE), caused by Echinococcus granulosus sensu lato, is a common zoonotic disease in Iran. Identifying various risk factors of this can pave the way for launching control and prevention programs, as well special health education target populations. For purpose, retrospective study investigated demographic characteristics human hydatidosis Hamedan. Methods: The r...

Background: Hepatitis C virus (HCV) is a blood-borne virus. It is a major global public health problem and can cause both acute and chronic hepatitis. The aim of this study was to report the epidemiological features of HCV infection and risk factors based on the data from Azar Cohort, East Azerbaijan province, Iran. Methods: The population of this study comprised the people in the age range of...

IN the years following 1858, when the British government formally assumed power over the whole of British India, the government of Bengal became concerned by reports of an epidemic of quinine-resistant fever occurring in the district of Burdwan in Lower Bengal. The mortality was so great that the population, the productivity of the land, and consequently the government revenue were greatly dimi...

Sir, Kala-azar, transmitted by sandflies was endemic in Assam until 1950, with three major epidemics between 1875 and 19501,2. Intensive insecticide spraying as part of National Malaria Eradication Programme eliminated the disease from Assam by mid 1950s, except for isolated case reports upto 19853. We recently diagnosed kalaazar in an adult male aged 43 years from Guwahati city, Assam, who was...

In 1950s the Government of India under National Malaria Eradication Programme (NMEP) now National Vector Borne Disease Control Programme, launched massive insecticidal spraying with DDT for malaria vector control and kala-azar came to a halt in Assam as a collateral benefit of malaria eradication programme. As a result, there were no further reports of kala-azar from the northeastern region exc...

OBJECTIVES Recent clinical data suggest that severe kala-azar (or visceral leishmaniasis) is an exaggerated innate immune response mediated by inflammatory cytokines, leading to a systemic inflammatory syndrome similar to what is observed in malaria, sepsis and other diseases. We tested this hypothesis by measuring serum cytokines in individuals with kala-azar. METHODS We compared patients wi...

INTRODUCTION The treatment of Indian tropical disease such as kala-azar is likely to be troublesome to the clinicians as AmpB- and miltefosine-resistant Leishmania donovani has been reported. The rationale behind designed a novel inhibitors of model of L. donovani enolase and performing a binding study with its inhibitors to gain details of the interaction between protein residues and ligand mo...

Post-Kala-Azar Dermal Leishmaniasis (PKDL) remains a major public health threat in Bangladesh. A cross-sectional study was carried out in Surya Kanta Kala azar Research Centre (SKKRC), Mymensingh, from January 2012 to July 2013 to evaluate the health seeking behaviour and the length of delay of PKDL management. The consecutive 200 diagnosed PKDL cases that got treatment in SKKRC hospital were s...