نتایج جستجو برای: haemophilus influenzae type b hib

تعداد نتایج: 2056403  

Journal: :Infection and immunity 2001
M Galdiero M D'Amico F Gorga C Di Filippo M D'Isanto M Vitiello A Longanella A Tortora

In the present study we observed that the Haemophilus influenzae type b (Hib) porin, among the different surface bacterial components, is involved in the pathophysiology of bacterial meningitis. This study demonstrates that inoculation of Hib porin into the fourth cerebral ventricle causes the simultaneous expression of interleukin-1alpha (IL-1alpha), tumor necrosis factor alpha (TNF-alpha), an...

Journal: :The American journal of tropical medicine and hygiene 1999
M C Wolff L H Moulton W Newcomer R Reid M Santosham

To understand the potential risk factors and protective factors for invasive Haemophilus influenzae type b (Hib) disease, we conducted a case-control study among Navajo children less than two years of age resident on the Navajo Nation. We analyzed household interview data for 60 cases that occurred between August 1988 and February 1991, and for 116 controls matched by age, gender, and geographi...

Journal: :Communicable diseases intelligence quarterly report 2008
Han Wang Shelley Deeks Amy Glasswell Peter McIntyre

The epidemiology of invasive Haemophilus influenzae type b (Hib) disease and its prevention by vaccination is reviewed for the period 1995 to 2005, comparing surveillance data for 1995-2000, when both PRP-OMP and HbOC vaccines were used, with 2000-2005, when only PRP-OMP vaccine was used. Over the whole time period, notifications of invasive Hib disease have declined dramatically. In the second...

2010
Felix Espinoza Miguel Tregnaghi Angela Gentile Katia Abarca Javier Casellas Alix Collard Inge Lefevre Jeanne-Marie Jacquet

BACKGROUND Diphtheria-tetanus-whole-cell pertussis (DTPw)-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV) and Haemophilus influenzae type B (Hib). To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HB...

Journal: :The Journal of pediatrics 2007
Michael E Pichichero Henry Bernstein Mark M Blatter Lode Schuerman Brigitte Cheuvart Sandra J Holmes

OBJECTIVE To evaluate the immunogenicity and safety of a diphtheria and tetanus toxoids, acellular pertussis, hepatitis B, and inactivated poliovirus-containing vaccine (DTaP-HepB-IPV) coadministered with pneumococcal 7-valent conjugate vaccine (PCV-7) and Haemophilus influenzae type b vaccine (Hib), with separate vaccines concurrently, or staggered (delayed) administration of PCV-7. STUDY DE...

Journal: :Communicable diseases intelligence 1997
A Herceg

Between July 1993 and June 1996, there were 412 cases of invasive Haemophilus influenzae type b (Hib) disease reported to the Hib Case Surveillance Scheme, 71% in children under the age of five years. Meningitis was the most frequent illness reported, followed by epiglottitis, septicaemia and pneumonia. There were 18 deaths. Thirty-four cases were classified as vaccine failures. The number of v...

Journal: :Journal of public health 2007
Edward I Broughton

BACKGROUND Haemophilus influenzae type B (Hib) causes significant morbidity and mortality in children under five years of age. A safe and effective vaccine is available but is not in general use in developing countries. This paper evaluates the cost-effectiveness of introducing Hib vaccine in Indonesia as an addition to the country's current DTP-Hepatitis B vaccination program. METHODS The ec...

Journal: :Journal of health, population, and nutrition 2004
Paul E Kilgore Batmunkh Nyambat

In the past 30 years, great strides have been made in immunizing infants and children routinely in developing countries under the Expanded Programme on Immunization. Despite this, the introduction of Haemophilus influenzae type b (Hib) vaccines has progressed rather slowly compared to previously-introduced vaccines for infant immunizations. This slower uptake has been attributed partly to the n...

Journal: :African health sciences 2007
Robert B D Otto Dennis T Crane Barbara Bolgiano

BACKGROUND Haemophilus influenzae type b (Hib) and Meningococcal group C (MenC) conjugate vaccines, which protect against otitis media, bacteremia and invasive diseases, including pneumonia and meningitis, are attractive candidates for combination, since they are both administered to infants and children. A Hib-MenC combination booster at 12 mo has recently been introduced in the U.K. OBJECTI...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008
Yeh Chen Lee Dominic F Kelly Ly-Mee Yu Mary P E Slack Robert Booy Paul T Heath Claire-Anne Siegrist Richard E Moxon Andrew J Pollard

BACKGROUND Despite the excellent immunogenicity of Haemophilus influenzae type b (Hib) conjugate vaccines, breakthrough cases of Hib disease still affect a small proportion of vaccinated children in the United Kingdom. We performed a retrospective study to compare the avidity of antibody directed against the Hib polysaccharide capsule (PRP) in children who experienced Hib vaccine failure in the...

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