Helicobacter pylori (H. pylori) is an ancient and persistent inhabitant of the human stomach that is closely linked to the development of gastric cancer (GC). . Emerging evidence suggests that H. pylori strain interactions with gastric epithelial cells subvert the best- characterized p53 tumour suppressor pathway. A high prevalence of p53 mutations is related to H. pylori infection. H. pylori a...

Helicobacter pylori infection, a highly prevalent pathogen, is a major cause of chronic gastritis and peptic ulcer and a risk factor for gastric malignancies. Antibiotics-based H. pylori eradication treatment is 90% effective. However, it is expensive and causes side effects and antibiotic resistance. Probiotics could present a low-cost, large-scale alternative solution to prevent or decrease H...

Helicobacter pylori (H. pylori) infection is etiologically associated with gastric cancer and peptic ulcer diseases which are both important public health burdens and which could be largely eliminated by H. pylori eradication. However, some investigators urge caution based on the hypothesis that eradication of H. pylori may result in an increase in the incidence of gastroesophageal reflux disea...

background: non-steroidal anti-inflammatory drug (nsaid) use and h pylori infection are two major causes of peptic ulcers. this study investigates the effect of h pylori infection and nsaids on gastroduodenal damages and bleeding (gib).   methods: 104 patients with acute gastrointestinal bleeding (gib) and 102 patients with dyspepsia without bleeding were studied. duodenal (du) and gastric ulce...

Background: The idiopathic peptic ulcers (IPU), or non-Helicobacter pylori nonsteroidal anti-inflammatory drugs (NSAIDs)-associated ulcers, are a serious therapeutic challenge. prevalence of IPU is increasing in some parts the world. Objectives: This study aimed to determine southeastern Iran. Methods: In this cross-sectional study, total 367 patients with active ulcer were diagnosed by endosco...

Background: Resistance of Helicobacter pylori?H. pylori? to antibiotics is increasing worldwide. In order understand the current situation antibiotic resistance in Nanjing and provide a reasonable basis for clinical selection cure H. Pylori. Objective: To investigate status Pylori area, analyze primary post-treatment pylori this area. Methods: During period from July 2017 December 2019, 1533 ga...

Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of the global human population. In order to successfully colonize the human stomach, H. pylori must initially overcome multiple innate host defenses. Remarkably, H. pylori can persistently colonize the stomach for decades or an entire lifetime despite development of an acquired immune response. This revi...

BACKGROUND Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrome. H. pylori infection and type 2 diabetes mellitus (T2DM) are associated with oxidative stress, this cross-relation between H. pylori induced infection in T2DM and oxidative damage is still debated. Th...