BACKGROUND Guided tissue regeneration (GTR) allows mesenchymal cells to repopulate the defects. However, there is limited information regarding the efficacy of different membranes. The present study was designed to histologically and histomorphometrically compare three collagen membranes in regenerative treatment of dehiscence defects in dogs. MATERIALS AND METHODS This 8 weeks experimental a...

Introduction Periodontal regeneration (PR) has provided the practitioner with a more conservative therapeutic strategy for the treatment of infrabony periodontal defects. In fact, PR not only helps reducing periodontal pocket depth (PPD), but it also allows to gain clinical attachment level (CAL) with minimal negative effects on gingival recession (REC), which is particularly important when tre...

The first critical stage in salamander or teleost appendage regeneration is creation of a specialized epidermis that instructs growth from underlying stump tissue. Here, we performed a forward genetic screen for mutations that impair this process in amputated zebrafish fins. Positional cloning and complementation assays identified a temperature-sensitive allele of the ECM component laminin beta...