OBJECTIVES In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma. Our aim was to assess blood flow response to topical glyceryl trinitrate (GTN) compared to placebo in SSc DUs, looking for differences in pathophysiology between fingertip and extensor lesions. METHOD This was a...

In dieser Arbeit wird ein Weg zur Erstellung von realistischen, weich wirkenden, virtuellen Gesichtsausdrücken vorgestellt. Um dies zu ermöglichen wurde eine modifizierte, von Waters 1987 entwickelte, Simulation der Gesichtsmuskeln mit einer Simulation der menschlichen Haut kombiniert. Die Hautsimulation basiert auf einer Reihe simpler Bedingungen und dient zur Faltenbildung im Gesicht. Für die...

T he electrocardiogram shown in Figure 1 was read by the computer as arm-lead reversal. Th e computer reading went on to say that no further analysis would be attempted. Th is clearly is a programming mistake because the precordial leads make the diagnosis. Although we would estimate that 95% of electrocardiograms with negative P, QRS, and T waves in lead I are due to armlead reversal, a small ...

PURPOSE The most common metric for comparing measured to calculated dose planes is a pass rate generated using percent difference, distance-to-agreement (DTA), or some combination of the two (e.g. gamma evaluation). The grid of analyzed points often corresponds to a dosimeter array with low areal-density of point detectors. This work examines the statistical uncertainty of planar dose compariso...

The aim of this investigation was to assess the applicability of lipid bilayer alteration using a combination of isopropyl myristate (IPM) and glyceryl monocaprylate (GEFA-C(8)) to the enhancement of pentazocine (PTZ) permeation through hairless mouse skin. The skin permeability of PTZ was enhanced by increasing the concentration of GEFA-C(8) up to 10% w/w in combination with IPM. Attenuated to...

OBJECTIVE Deficient reward processing has gained attention as an important aspect of ADHD, but little is known about reward-based decision-making (DM) in adults with ADHD. This article summarizes research on DM in adult ADHD and contextualizes DM deficits by comparing them to attention deficits. METHOD Meta-analytic methods were used to calculate average effect sizes for different DM domains ...

This document describes for the historical record the motivation behind the Datagram Congestion Control Protocol (DCCP), an unreliable transport protocol incorporating end-to-end congestion control. DCCP implements a congestion-controlled, unreliable flow of datagrams for use by applications such as streaming media or on-line games. Floyd, et al. Informational [Page 1] RFC 4336 Problem Statemen...

370 Ann Dermatol Received February 14, 2012, Revised September 12, 2012, Accepted for publication October 6, 2012 Corresponding author: Weon Ju Lee, Department of Dermatology, Kyungpook National University School of Medicine, 130 Dongdeok-ro, Jung-gu, Daegu 700-721, Korea. Tel: 82-53-420-5837, Fax: 82-53-426-0770, E-mail: [email protected] This is an Open Access article distributed under the ter...