We denote D the set of parameters (of course the existence of the Cayley transform and cross action tables imply that the set D has already been enumerated, and thus identified with a set [0,M [ of integers.) We let M be the free A-module generated by D, where A = Z[v, v−1], and we write q = v2. We replace the canonical basis (Tδ)δ∈D of M by tδ = v Tδ, where l : D → N is the length function (al...

Mammary gland involution is characterized by extensive apoptosis of the epithelial cells. At the onset of involution, Stat3 is specifically activated. To address the function of this signaling molecule in mammary epithelial apoptosis, we have generated a conditional knockout of Stat3 using the Cre-lox recombination system. Following weaning, a decrease in apoptosis and a dramatic delay of invol...

During mammary gland involution, the epithelial mesenchymal transition (EMT) process plays an important role in tissue remodelling and in the termination of milk production. Transforming growth factor β (TGFβ) has been known as a central inducer to EMT and contributor to the mammary gland involution. However, the whole mechanism has accomplished the EMT process in mammary gland is still unclear...

Coxeter-Petrie complexes naturally arise as thin diagram geometries whose rankthree residues contain all of the dual forms of a regular algebraic mapM. Corresponding to an algebraic map is its classical dual, which is obtained simply by interchanging the vertices and faces, as well as its Petrie dual, which comes about by replacing the faces by the so-called Petrie polygons. G. A. Jones and J. ...

Abstract The affine matrix-ball construction (abbreviated AMBC) was developed by Chmutov, Lewis, Pylyavskyy, and Yudovina as an generalization of the Robinson–Schensted correspondence. We show that AMBC gives a simple way to compute distinguished involution in each Kazhdan–Lusztig cell symmetric group. then use give 1st known canonical presentation for asymptotic Hecke algebras extended groups....

We show that the odd-indexed derived Witt groups of a semilocal ring with trivial involution vanish. We show that this is wrong when the involution is not trivial and we provide examples.

The mammary gland undergoes extensive tissue remodeling and cell death at the end of lactation in a process known as involution. We present evidence that the prolactin-activated transcription factor signal transducer and activator of transcription 5a (Stat5a) has a crucial role in the regulation of cell death during mammary gland involution. In a transforming growth factor-alpha transgenic mous...

Mammary gland involution is the most dramatic example of physiological cell death. It occurs through an initial phase of lysosomal-mediated cell death (LCD) followed by mitochondrial-mediated apoptosis. Zinc (Zn) activates both LCD and apoptosis in vitro. The Zn transporter ZnT2 imports Zn into vesicles and mitochondria and ZnT2-overexpression activates cell death in mammary epithelial cells (M...

BACKGROUND Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary gland development has not been studied. To this end, we generated Igfbp7-null mice and examined th...