Foreign body granuloma reaction is a tissue response to some extraneous materials which incite a characteristic pattern of granulomatous reaction. Several cases of foreign body granulomas on the face have been reported, especially after the injection of dermal fillers. Oleoma or paraffinoma is defined as a foreign body granuloma resulting from the injection of oily substances into the skin or s...

chronic granulomatous disease represents a group of inherited disorders of phagocytic system wherein recurrent infections are seen at different sites especially in the respiratory system. to determine the clinical spectrum of respiratory manifestations in chronic granulomatous disease patients, in this retrospective study, we used data from iranian primary immunodeficiency registry. the diagnos...

Normal human eosinophils possess appreciable intrinsic candidacidal activity. The leukocyte microbicidal deficiency of chronic granulomatous disease is manifested by eosinophils as well as by neutrophils and monocytes.

Childhood granulomatous periorificial dermatitis (CGPD), also known as facial Afro-Caribbean childhood eruption (FACE), is a distinctive granulomatous form of perioral dermatitis. It is a condition of unknown etiology, characterized by monomorphous, small, papular eruptions around the mouth, nose and eyes that histopathologically show a granulomatous pattern. It affects prepubescent children of...

conclusions alternariasis or similar cases may be increased due to the increased number of immunosuppressed patients. from this point of view, skin lesions in these patients must be planned and microbiologically evaluated considering the molds. case presentation we reported a case of wound infection induced by alternaria spp. in a renal transplant patients. the main interest in this case was th...

Phagocyte NADPH oxidase plays a key role in pathogen clearance via reactive oxygen species (ROS) production. Defects in oxidase function result in chronic granulomatous disease with hallmark recurrent microbial infections and inflammation. The oxidase's role in the adaptive immune response is not well understood. Class II presentation of cytoplasmic and exogenous Ag to CD4(+) T cells was impair...

Pneumocystis jirovecii pneumonia (PJP) in patients with HIV infection can, in rare cases, present with pulmonary nodules that histologically involve granulomatous inflammation. This report describes an intriguing case of granulomatous PJP with pulmonary nodules after commencing antiretroviral therapy (ART) in an HIV-infected patient without respiratory signs or symptoms. Diagnosis of granulomat...

The parenchymal lung diseases caused by metal inhalation include interstitial fibrosis, giant cell interstitial pneumonitis, chemical pneumonitis, and granulomatous disease, among others. We reported two cases of granulomatous lung disease with occupational exposure to metal dusts other than beryllium. They had worked in the battery manufacturing industry for 7 years and in an aluminum-processi...