protonation of the reactive intermediate produced in the  reaction between trimethyl phosphite and dimethyl acetylenedicarboxylate or diethyl acetylenedicarboxylate by resorcinol, 5-methylresorcinol, 2,5-dihydroxyacetophenone, 4-chloro-2-methylphenol, 4-chloro-3,5-dimethy-lphenol, 4-hydroxypyridine, 2-hydroxypyridine, 3-hydroxypyridine, or 8-hydroxyquinoline leads to vinylphosphonium salts, whi...

2-Functionalised aromatic monoaldehydes were synthesised in good to excellent yields by reacting 4-bromo-2-fluorobenzaldehyde with different secondary amines and phenol. The Suzuki-coupling reaction of the newly functionalised aromatic monoaldehydes with 4-formylphenylboronic acid afforded the corresponding 2-functionalised-4,4'-biphenyldialdehydes in good yields (47-85%). The [3+3]-cycloconden...

The palladium-catalyzed conjugate addition (Michael addition) of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones, in particular 3-methyl cyclopent-2-enone and 3-methyl cyclohex-2-enone, is reported. With an achiral bipyridine-based palladium catalyst, good yields are obtained with a variety of ortho-substituted arylboronic acids. In the asymmetric version, good to very hi...

La(OAc)3 has been used as an efficient catalytic system for the synthesis of quinoxalines. This method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for five cycles with consistent activity.

Carthamin, the natural dye of carthamus tinctorius (Golrang) was separated by soxhlet extraction and further purified in good yields. Its mordant dyeing of wool, using potassium dichromate as mordant, showed a high washing fastness (above 4). Mordanting by "sweet chrome", "sour chrome", and "reduced chrome" proved that last one to be superior.

The 1:1 reactive intermediates produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates were trapped with 2-thioxothiazolidin-4-one to generate to highly functionalized ketenimines. A series of new 2-thioxothiazolidin-4-one derivatives were synthesized in moderate yields. The advantages of the present method include good functional group tolerance and simple experi...

Vilsmeier-Haack reaction of 2,3,3-trimethyl-3H-benzo[g]indole, then aqueous basic work-up, leads to benzo[g]indol-2-ylidene- malondialdehydes. These react with various arylhydrazines and quinolin-2-ylhydrazine to form 3,3-dimethyl-2-(1-aryl-1H-pyrazol-4-yl)- 3H-benzo[g]indoles in good yields.

      Some amide derivatives have been synthesized by the reaction of corresponding nitriles with potassium tert-butoxide as a nucleophilic oxygen source under ultrasonic irradiation. This new methodology provides good to excellent yields in short reaction times (15-90 min) at room temperature.

In this research, different alcohols and phenols are subjected to the reaction with HMDS in the presence of ionic liquid and silica-supported catalysts. Silylation was accomplished under mild reaction conditions at room temperature in short reaction times and good to excellent yields.

Sulfonic acid functionalized SBA-15 as a nanoporous acid catalyst was used in the synthesis of 2-Aryl benzoxazoles 4 by the condensation of 2-aminophenol 1 and benzoyl chlorides 2 under microwave irradiation in solvent free reaction conditions. The advantages of this methodology are good product yields (60-98%), being environmentally benign, short reaction times and easy work up.