نتایج جستجو برای: goldsilver bi

تعداد نتایج: 46275  

2018
Kai Wang Dongmei Zhang Yan Liu Xuan Wang Jiantong Zhao Tingting Sun Tingting Jin Baoli Li Janak L. Pathak

BACKGROUND Traditional Chinese medicine (TCM) formula Bi-Qi capsule (Bi-Qi) is a commonly prescribed drug to treat rheumatoid arthritis (RA). However, the mechanism of Bi-Qi-mediated amelioration of RA pathogenesis is still a mystery. Collagen induced arthritis (CIA) in rats is an established model that shares many similarities with RA in humans. In this study we investigated the effect of Bi-Q...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Kalliopi Thanopoulou Apostolia Fragkouli Fotini Stylianopoulou Spiros Georgopoulos

Scavenger receptor class B type I (SR-BI) is a high-density lipoprotein receptor that regulates cholesterol efflux from the peripheral tissues to the liver. SR-BI has been identified on astrocytes and vascular smooth muscle cells in Alzheimer's disease brain and has been shown to mediate adhesion of microglia to fibrillar amyloid-β (Aβ). Here we report that SR-BI mediates perivascular macrophag...

Journal: :The Journal of biological chemistry 2009
Ling Guo Zhiqing Song Mengting Li Qingan Wu Dan Wang Hong Feng Philip Bernard Alan Daugherty Bin Huang Xiang-An Li

Sepsis is a leading cause of death that is characterized by uncontrolled inflammatory response. In this study, we report that scavenger receptor BI (SR-BI), a high density lipoprotein receptor, is a critical survival factor of sepsis. We induced sepsis using an established septic animal model, cecal ligation and puncture (CLP). CLP induced 100% fatality in SR-BI-null mice but only 21% fatality ...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2011
Suzanne J A Korporaal Illiana Meurs Arnaud D Hauer Reeni B Hildebrand Menno Hoekstra Hugo Ten Cate Domenico Praticò Jan-Willem N Akkerman Theo J C Van Berkel Johan Kuiper Miranda Van Eck

OBJECTIVE Scavenger receptor BI (SR-BI) is a cell surface receptor that promotes the selective uptake of cholesteryl esters from high-density lipoprotein (HDL) by the liver. In mice, SR-BI deficiency results in increased plasma HDL cholesterol levels and enhanced susceptibility to atherosclerosis. The aim of this study was to investigate the role of SR-BI deficiency on platelet function. METH...

2017
Yuxin Wang Guang Cheng See Leng Tay Yunxia Guo Xin Sun Wei Gao

In this study we investigated the effects of Bi addition on the microstructure and mechanical properties of an electrodeposited nanocrystalline Ag coating. Microstructural features were investigated with transmission electron microscopy (TEM). The results indicate that the addition of Bi introduced nanometer-scale Ag-Bi solid solution particles and more internal defects to the initial Ag micros...

Journal: :International journal of clinical and experimental pathology 2015
Bingjie Lu Yu Li Hua Li Yingmei Zhang Jin Xu Lihong Ren Songbin Fu Yi Zhou

Bax inhibitor-1 (BI-1) is a novel anti-apoptotic protein. While the effect of BI-1 on apoptosis has been extensively studied, less is known about how BI-1 is related to oncogenesis and the progression, particularly, the invasion and metastasis of cancer. In this study, we investigated the expression and function of BI-1 in human non-small cell lung cancer (NSCLC). RT-PCR and immunohistochemistr...

Journal: :PLoS Pathogens 2009
Marlène Dreux Viet Loan Dao Thi Judith Fresquet Maryse Guérin Zélie Julia Géraldine Verney David Durantel Fabien Zoulim Dimitri Lavillette François-Loïc Cosset Birke Bartosch

HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by coordinated interactions with the scavenger receptor class B type I (SR-BI), a major receptor of high-density lipoprotein (HDL), the CD81 tetraspanin, and the tight junction protein Claudin-1, ultimately leading to upta...

2010
Robert J Tait Kaarin J Anstey Peter Butterworth

BACKGROUND Traumatic or serious brain injury (BI) has persistent and well documented adverse outcomes, yet 'mild' or 'moderate' BI, which often does not result in hospital treatment, accounts for half the total days of disability attributed to BI. There are currently few data available from community samples on the incidence and correlates of these injuries. Therefore, the study aimed to assess...

Journal: :Cancer research 2011
Damian Wild Michael Frischknecht Hanwen Zhang Alfred Morgenstern Frank Bruchertseifer Julie Boisclair Anne Provencher-Bolliger Jean-Claude Reubi Helmut R Maecke

Recurrent prostate cancer presents a challenge to conventional treatment, particularly so to address micrometastatic and small-volume disease. Use of α-radionuclide therapy is considered as a highly effective treatment in such applications due to the shorter range and exquisite cytotoxicity of α-particles as compared with β-particles. (213)Bi is considered an α-emitter with high clinical potent...

2001
Sang Hoon Shin Duk Young Jeon Kyung Soo Suh

Bismuth doped yttrium niobate (YNbO4:Bi) is a potential blue phosphor for field emission displays application. It is observed after introducing Bi ions that cathodoluminescence efficiency of YNbO4:Bi becomes lower than that of YNbO4 . From the calculations of critical distance (RC) of energy transfer and Huang–Rhys parameter (SHR) of YNbO4:Bi, it is found that the energy transfer by a dipolar-t...

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