نتایج جستجو برای: glyburide

تعداد نتایج: 2213  

2016
Daniel Asfaw Erku Abebe Basazn Mekuria Abdrrahman Shemsu Surur Begashaw Melaku Gebresillassie

PURPOSE This study was aimed at assessing the extent of dispensing prescription-only medications without a prescription in community drug retail outlets (CDROs) of Addis Ababa, Ethiopia. METHODS A descriptive cross-sectional observational study design was used to sample 31 pharmacies, 25 drug stores, and two rural drug vendors from August 11, 2015, to October 21, 2015, through a simple random...

Journal: :The Journal of pharmacology and experimental therapeutics 2002
Murali Gopalakrishnan Steven A Buckner Kristi L Whiteaker Char-Chang Shieh Eduardo J Molinari Ivan Milicic Anthony V Daza Rachel Davis-Taber Victoria E Scott Donna Sellers Russ Chess-Williams Christopher R Chapple Yi Liu Dong Liu Jorge D Brioni James P Sullivan Michael Williams William A Carroll Michael J Coghlan

Alterations in the myogenic activity of the bladder smooth muscle are thought to serve as a basis for the involuntary detrusor contractions associated with the overactive bladder. Activation of ATP-sensitive K(+) (K(ATP)) channels has been recognized as a potentially viable mechanism to modulate membrane excitability in bladder smooth muscle. In this study, we describe the preclinical pharmacol...

Journal: :American journal of physiology. Endocrinology and metabolism 2007
Ananda Basu Nisha Charkoudian William Schrage Robert A Rizza Rita Basu Michael J Joyner

Sulfonylureas (SU) with glucagon-like peptide-1 (GLP-1)-based therapy are an emerging therapeutic combination for type 2 diabetes. Prior human studies have hinted at endothelial effects of GLP-1 and SU. To study the endothelial effects of GLP-1 per se and to evaluate the modulatory effects, if any, of SU agents on GLP-1-induced changes in endothelial function, healthy, nondiabetic, normotensive...

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