HNE 4-Hydroxy-2-nonenal 5-HT 5-Hydroxytryptamine ATPase Adenosine triphosphatase ALA Alpha-lipoic acid DNA Deoxyribonucleic acid GABA Gamma-amino butyric acid GPX Glutathione peroxidase GAP43 Growth-associated protein 43 NAD+ Nicotinamide adenine dinucleotide oxidized NADP+ Nicotinamide adenine dinucleotide phosphate oxidized NADHP Nicotinamide adenine dinucleotide phosphate reduced NADH Nicoti...

Associated gas flaring has several consequences on the environment. This study was aimed at assessing impact of soil enzymes and plant antioxidant activities from flare-bearing communities in Nigeria. Soil samples were obtained farmlands Ukwa West Izombe sites, as well unpolluted site Olokoro (used control). The level urease, dehydrogenase, phosphatases, lactate dehydrogenase (LDH) selected pla...

The aim of this study was to determine the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx), total antioxidant status (TAS) and accumulation of Hsp70 in porcine ovarian granulosa cells after deoxynivalenol (DON) and zearalenone (ZEA) exposure in vitro. Porcine ovarian granulosa cells were incubated with DON/ZEA administrations as follows: group A (10/10 ng/mL), group B (100/...

Selenium status was determined in an endemic-goiter area and in a control area of Zaire. Compared with the reference values of a noniodine-deficient area, serum selenium in subjects living in the core of the northern Zaire endemic-goiter belt (Karawa villages) was seven times lower in 52 school-children and similarly low in 23 cretins; erythrocyte glutathione peroxidase (RBC-GPX) was five times...

Glutathione peroxidase (GPx) is a family of antioxidant enzymes that reduce reactive oxygen species (ROS), thereby constituting a primary defence system against oxidative stress. Of the five characterised isoforms of GPx found in mammals, GPx1 is the predominant intracellular form and GPx3 is the predominant form found in the extracellular space1. Experimental studies have demonstrated that def...

abstract in the present set of investigations, the anti-mutagenic and anti-cytotoxic effects of aqueous rosemary leaves extract (re) beside the dose dependency of these effects on male mice bone marrow and germ cells have been evaluated using in vivo cytogenetic, histopathologic and apoptotic assays, as well as biochemical analysis. doxorubicin (dxr), a well-known mutagen and cytotoxic agent, w...

Today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-ZrO2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. However, there are some reports implying that use of nano-ZrO2 is associated with cytotoxic effects like inhibiting the cell proliferation, DNA damage and apoptosis. In the present study, we examined whether nano-ZrO2 alters ...

Blood platelets are considered to be a peripheral marker in schizophrenia and other psychiatric disorders. Oxidative stress in schizophrenia may be responsible for changes in platelet metabolism and function; therefore, the aim of this study was to examine and compare the generation of superoxide anions and activity of an antioxidant enzyme (glutathione peroxidase [GPx]) in blood platelets in p...

AIMS Levels of antioxidants such as folic acid and selenium decrease in dams exposed to ethanol during gestation and lactation, affecting their antioxidant status, their reproductive function and consequently the health of their progeny. We will study whether a Se (0.5 p.p.m.) plus folic acid (8 p.p.m.) supplemented diet administered to ethanol-exposed dams and male rats prevents the effects pr...

BACKGROUND Hepatitis is a health problem affecting millions of people worldwide and it is the major risk factor for liver cirrhosis. In India, many plants are used to treat hepatitis. But little is known about the effects of (-)-epicatechin a bioactive compound of Phyllanthus niruri (PN) in hepatitis rats. OBJECTIVE The present study was designed to explore the antioxidant property of (-)-epi...