visceral leishmaniasis is the second most common cause of fever of unknown origin in our study. this disease is not common in adults, although it's endemic among the pediatric age group. the majority of the affected individuals were young. high grade spiking fever, chills and splenomegaly were unique findings. other common findings were neutropenia, anemia, abnormal liver function tests, s...

Leishmaniasis is one of the major health problems in Iran. Although the incidence of visceral leishmaniasis (VL) is reported almost everywhere, the northwestern Iran is one of the major endemic regions.To do this study, clinical, laboratory as well as disease characteristics of children admitted to Children Cure and Health Hospital, Tabriz University of Medical Sciences, were examined as the re...

In our endemic area of Leishmania (Viannia) braziliensis (L(V)b) transmission4 we ocasionally see disseminated disease without anergy1. Sometimes this is associated with mucosal involvement3. Here we report the observation of mucosal recovery with residual skin lesions activity in two such patients. Skin biopsy histology showed the parasite in both cases. Patient LTCP 10061, a 42 year old male ...

The parasites of genus Leishmania are the causative agents of one of the most widespread and devastating diseases. According to follow-up data, these medications may provoke adverse drug reactions, drug resistance, relapse as well as financial burden. The mechanism of action of opioid drugs are primarily exerted via transmembrane G-protein coupled receptors. One of the potent synthetic immunomo...