OBJECTIVE The overall goal of this study was to evaluate the usability of the susceptibility weighted imaging (SWI) in (1) assessment of iron deposition to enhance our ability to detect PD in the early phase and (2) in estimation of the degree of PD. PATIENTS AND METHODS SWI scans were carried out in 54 patients with PD (18 patients with the Hoehn-Yahr scale < 1.5 and 36 patients with the Hoe...

In the D-Grid project BIS-Grid we developed the BIS-Grid Workflow Engine in order to utilize a common WS-BPEL workflow engine for scientific workflow execution in WSRF-based Grid infrastructures. The BIS-Grid Workflow Engine itself is built on the Grid middleware UNICORE 6 to benefit from its security mechanisms and to automatically gain interoperability with UNICORE 6-based Grid infrastructure...

In order to investigate the sequence and pattern of neurodegeneration in Huntington's disease, the distribution and density of cannabinoid CB(1), dopamine D(1) and D(2), adenosine A(2a) and GABA(A) receptor changes were studied in the basal ganglia in early (grade 0), intermediate (grades 1, 2) and advanced (grade 3) neuropathological grades of Huntington's disease. The results showed a sequent...