نتایج جستجو برای: gliclazide
تعداد نتایج: 499 فیلتر نتایج به سال:
Since their introduction in clinical practice in the 1950's, Sulfonylureas (SUs) have remained the main-stay of pharmacotherapy in the management of type 2 diabetes. Despite their well-established benefits, their place in therapy is inappropriately being overshadowed by newer therapies. Many of the clinical issues associated with the use of SUs are agent-specific, and do not pertain to the clas...
Hypoglycaemia is a common, potentially fatal, yet preventable problem. The aetiology of hypoglycaemia is variable, but druginduced hypoglycaemia remains the commonest cause. Determining the aetiology of hypoglycaemia poses little difficulty in patients known to be taking oral hypoglycaemic agents (OHAs). However, it becomes a challenge in those without a history of such exposure. The Hospital A...
Methods of 1-[2-(1H-tetrazol-5-yl)-R(1)-phenyl]-3-R(2)-phenyl(ethyl)ureas and R(1)-tetrazolo[1,5-c]quinazolin-5(6H)-ones synthesis were designed. IR, LC-MS, (1)H NMR, and elemental analysis data evaluated the structure and purity of the obtained compounds. Different products, depending on the reaction conditions, were distinguished and discussed. The preliminary hypoglycemic activity of 36 synt...
Dapagliflozin is the first novel SGLT2 inhibitor for treatment of Type 2 diabetes. The aim this study was to evaluate its effectiveness and safety in a real-life clinical setting. We analyze data from four hospitals on patients initiated dapagliflozin. HbA1c, weight daily insulin dosage recorded at baseline 6 months follow-up.229 received At baseline, mean HbA1c 82mmol/mol(186) 102 kg(n=159).Th...
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