Purpose Paxillin regulates cell-cell adhesion, and altered Paxillin expression has been associated with human carcinogenesis. This study analyzed the association between Paxillin expression in prostate cancer (PCa) tissues with clinicopathological features, lymph node metastasis and biochemical PCa recurrence. Methods A total of 386 tissue specimens from PCa patients who received radical prosta...

results there were 39 cases with lymph node metastasis in 59 malignant tumors, and 0 cases in 6 benign follicular type tumors. the staining scores by jt-95 of the 39 tumors with lymph node metastasis were 5+ in eight cases and 6+ in 31 cases. on the other hand, the scores of 20 malignant tumors without lymph node metastasis were < 4+ in all of the cases. in the co-cultured assay, numerous adhes...

follicular dendritic cells or dendritic reticulum cells are important components of the immune system essential for antigen presentation. malignancies arising from these cells are uncommon and the first case was reported in 1986. the most common sites of follicular dendritic cell sarcomas are lymph nodes, especially cervical, axillary and mediastinal regions, but extranodal sites including head...

kawasaki disease is believed to be the commonest vasculitis of medium vessels in asian children. however, the majority of children with kawasaki disease continue to remain undiagnosed perhaps because of the lack of awareness amongst pediatricians. the clinical features of kawasaki disease can be confused with other common conditions such as scarlet fever, stevens johnson syndrome, measles fever...

discussion benign metastasizing pleomorphic adenoma is a rare and controversial but distinct clinical entity. although the definition of the term benign precludes metastatic disease, these tumors do not demonstrate any malignant features yet metastasized to distinct sites. it remains to be determined whether this benign metastasizing pleomorphic adenoma is really low grade salivary malignancy. ...

BACKGROUND Physicians in daily practice frequently attend children who present an increase in lymph node size. Care should be taken to determine which children require biopsy. Our objective was to analyze the usefulness of the peripheral lymph node biopsy in pediatric diagnosis. METHODS We reviewed histological reports of 364 lymph node biopsies. Variables were age, sex, lymphadenopathy evolu...

Lymph node reactive hyperplasia, caused by specific infectious etiologic factors, represents the most frequent cause of enlarged peripheral lymph nodes. The main infectious agents are viruses, pyogenic bacteria, mycobacteria, fungi and protozoa that may determine unspecific or specific pathological entities, such as cat-scratch disease, toxoplasmosis or infectious mononucleosis. Lymph node fine...

Brunner's gland hyperplasia is a benign tumor of the duodenum and it is rarely associated with clinical symptoms. We report on a 64-yr-old man with Brunner's gland hyperplasia who had undergone a duodenocephalo-pancreatectomy. The reason is that he presented upper gastrointestinal obstructive symptoms and the esophagogastroduodenoscopic finding revealed the lesion to be an infiltrating type mas...

castleman disease (cd) is a rare, lymphoproliferative disorder of uncertain etiology. we are reporting on two cases of castleman disease. both patients were female. this disease can be found wherever lymph nodes are present. we have reported two unusual cases of castleman disease. a 29- year old woman was referred for evaluation because of a cervical lymph node, weight loss and night sweats. th...