OBJECTIVE The development of diabetic ketoacidosis in pregnancy is a medical emergency, requiring treatment in an intensive care setting. Both the mother and the fetus are at risk for significant morbidity and mortality. Physiologic changes unique to pregnancy provide a background for the development of diabetic ketoacidosis. An understanding of these physiologic changes assists in the manageme...

OBJECTIVE To determine the concentration of plasma leptin and other metabolic hormones in offspring of diabetic and none diabetic mothers after 2 weeks of age. The relationship between leptin and metabolic hormones was also investigated. METHODS Included in the study were 79 newborns from the Neonatal Unit at King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia from January 20...

This review highlights factors of importance for the clinical care of pregnant women with pregestational diabetes and microalbuminuria or diabetic nephropathy with particular focus on the role of intensive antihypertensive treatment during pregnancy. Most information in the literature comes from women with type 1 diabetes and diabetic nephropathy, but this is probably also valid for women with ...

Gestational diabetes mellitus (GDM) is an impaired fasting glucose condition during pregnancy. Adiponectin is a polypeptide hormone that is extensively released by adipocytes which regulates energy homeostasis and carbohydrate and lipid metabolism. In addition, adiponectin has antidiabetic and anti-inflammatory properties. The aim of our research was to study about the relationship of adiponect...

This paper considers studies aimed at identifying markers of genotoxicity (chromosomal aberrations, micronuclei, and DNA damage assessed by the comet assay) in patients with both gestational diabetes mellitus (GDM) type 1 2 (T1DM T2DM, respectively), as well possible changes levels these genotoxic under influence medicines nutritions. Patients T2DM are characterized an increased level markers. ...

I appreciate the heavy work conducted by Dr. Saleh and all his colleagues1 in their recent paper. There has been a rise in the prevalence of large newborns over a few decades in many parts of the world. In current obstetrics, the macrosomic fetus represents a frequent clinical challenge.2 Various studies have shown a significant increase in the frequency of complications in the course of pregna...

maternal diabetes has teratogenic effects on the evolution of the fetal cardiovascular system; as a consequence, cardiovascular malformations are the most common anomalies in infants of diabetic mothers. the present study focuses on the association of all types of diabetes in mothers with the incidence of congenital cardiovascular malformations in their infants. in this retrospective case-contr...

BACKGROUND Pre-gestational diabetes (PGDM) is a significant cause of neonatal morbidity and mortality. Delayed villous maturation (DVM) is a placental diagnosis with increased risk of perinatal mortality. AIMS This study aimed to prospectively look at the incidence of DVM in a PGDM population compared to non-diabetic controls. Additionally, we analysed antenatal ultrasound and clinical marker...

Abstract Background Gestational diabetes mellitus (GDM) is the most frequent and prevalent medical condition in pregnancy. Well-controlled GDM results reduction of these unfavorable outcomes. Aim To assess women’s knowledge many elements gestational mellitus, including general awareness condition, risk factors, diabetic patients’ diets, consequences among women governorate Sohag. Patients metho...