Objective. To identify factors predicting the need for insulin therapy in pregnancies complicated by gestational diabetes mellitus (GDM). Methods. A total of 1352 patients with GDM diagnosed by the 75-g/2-h oral glucose tolerance test (OGTT) were enrolled in this study. Univariate and multivariate analysis were performed; receiver operating characteristics (ROC) were also drawn. Results. There ...

OBJECTIVE Gestational diabetes mellitus (GDM), defined by two abnormal glucose values on a 3-h oral glucose tolerance test (OGTT), is associated with insulin resistance and a low serum concentration of adiponectin. The metabolic implications of impaired glucose tolerance (IGT) of pregnancy (i.e., a single abnormal value on an OGTT), however, are not well established. We sought to evaluate the m...

Objective: Gestational diabetes mellitus (GDM) is the most common endocrine disorder in pregnancy and number of pregnant women resistant to oral glucose tolerance test (OGTT) has increased significantly recent years. In this study, we investigated extent resistance OGTT screening followed-up our hospital effect situation on newborn.
 Material Method: Pregnant their babies who were followed...

OBJECTIVE This article tests the hypothesis that women with impaired glucose tolerance (IGT) have the same pregnancy outcomes as those of their counterparts with normal glucose tolerance. RESEARCH DESIGN AND METHODS From December 1998 to December 1999, 84 of 90 antenatal care base units (ACBUs) under the Tianjin Antenatal Care Network in China participated in the first screening program for g...

INTRODUCTION Adopting the modified International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria for diagnosing gestational diabetes mellitus (GDM) will increase the prevalence of GDM resulting in increased resource utilisation and an unknown effect on clinical outcomes. AIMS To determine the prevalence of GDM by the modified IADPSG criteria and compare characteristics an...

OBJECTIVE Progranulin (PGRN) was recently introduced as a novel marker of chronic inflammatory response in obesity and type 2 diabetes capable of directly affecting the insulin signaling pathway. This study aimed to investigate the role of PGRN in gestational diabetes mellitus (GDM), which is regarded as a model for early type 2 diabetes. METHODS PGRN serum levels were measured in 90 pregnant...

BACKGROUND AND INTRODUCTION Diabetes is increasing at alarming rate among Indians especially South Indians with prevalence of diabetes mellitus (PODM) varying in populations of different regions. This study assesses PODM in three geographical areas, namely: tribal, semi-urban, and urban, and to compare the diabetes risk in northern coastal districts of Andhra Pradesh state in India. METHODOLO...

OBJECTIVE The purpose of this study was to investigate the insulin sensitivity and visceral fatness in women with previous gestational diabetes mellitus (GDM), who are prone to develop type 2 diabetes. RESEARCH DESIGN AND METHODS A 75-g oral glucose tolerance test (OGTT) performed 1 year postpartum identified 21 GAD(-) women with previous GDM and impaired glucose tolerance (GDM-IGT). Sixty ag...

OBJECTIVE The aim of this study was to investigate the prevalence of gestational diabetes mellitus (GDM) and risk factors for the development of GDM in pregnant women in Tianjin, China, where the prevalence of GDM is still unknown. STUDY DESIGN AND METHODS A total of 9,471 pregnant women living in the six urban districts of Tianjin, China, took part in the initial screening between December 1...

Hypertension guidelines advise limiting the dose of thiazide diuretics and avoiding combination with β-blockade, because of increased risk of diabetes mellitus. We tested whether changes in the 2-hour oral glucose tolerance test could be detected after 4 weeks of treatment with a thiazide and could be avoided by switching to amiloride. Two double-blind, placebo-controlled, crossover studies wer...