BACKGROUND & AIMS Common IL28B locus polymorphisms (SNPs rs8099917 and rs12979860) have been reported to affect peg-interferon plus ribavirin combination therapy (PEG-RBV) for hepatitis C virus (HCV) genotype 1b, but few reports have examined their effect on other two common genotypes, 2a and 2b. METHODS We analyzed predictive factors for sustained virological response (SVR) in a retrospectiv...

Genotype environment interaction and stability performance were investigated on grain yield per plot in eight environments during Rabi (here, rabi means that a crop has been grown season: crops are sown winter harvested spring the Indian subcontinent) 2019–2020 2020–2021 using 100 diverse wheat genotypes. Research was conducted at Chaudhary Charan Singh Haryana Agricultural University, Hisar, I...

Bronchomalacia in adults is rare. A case is reported here of a 65-year-old man with severe cough and mucostasis, caused by a benign bronchomalacia of the ventral wall of the left main bronchus. This was treated successfully with the insertion of a silicone Dumon stent as an alternative to surgical bronchoplasty.

among the lesions induced by chemotherapeutic drugs, dna double-strand breaks (dsb) are considered the most serious ones that can result in cell death, if it is not properly repaired. homologous recombination (hr) pathway is the main system for dsb repair and xrcc3 has a key role in this pathway. protein activity can be affected by the xrcc3 polymorphism. thus, in this study, the association be...

OBJECTIVE From a review of published information on genetic association studies, a meta-analysis was conducted to determine the influence of the genes κ-casein (CSN3) and β-lactoglobulin (LGB) on milk yield traits in Holstein, Jersey, Brown Swiss, and Fleckvieh. METHODS The GLIMMIX procedure was used to analyze milk production and percentage of protein and fat in milk. Models included the mai...

UNLABELLED Background and rationale of the study. Hepatitis C infection is very common among injection drug users(IDUs). In clinical practice there is reluctance to treat IDUs, because considered difficult-to-treat. Aim of this study was to evaluate the response to antiviral treatment in IDUs compared to non-IDUs. MAIN RESULTS In this observational retrospective study, 204 non cirrhotic patie...

Two patients with an intraluminal carcinoid tumour obstructing the right main bronchus in one, and the left main bronchus in the other, resulting in unilateral increased transradiancy from hypoperfusion of the lung, are described. Resection of the tumours and reconstruction of bronchial continuity was followed by return of perfusion to normal between three and 18 months after the operation. The...

Foreign bodies [FB] in the bronchus are important causes of morbidity and mortality in paediatric age group and pose diagnostic and therapeutic challenges. Inert and smooth foreign bodies are prone for migration from one side to other due to minimal inflammatory process and easy mobility. Herein we are reporting a case of electric bulb aspiration which migrated from right main bronchus to left ...

BACKGROUND Cholesteryl ester transfer protein (CETP) plays a main role in high-density lipoprotein metabolism. CETP gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (HDL-C) concentrations. The aim of this study was to determine the association of CETP -629C/A and I405V polymorphisms with coronary artery disease (C...

Although personalised nutrition is frequently considered in the context of diet–gene interactions, increasingly, personalised nutrition is seen to exist at three levels. The first is personalised dietary advice using Internet-delivered services, which ultimately will become automated and which will also draw on mobile phone technology. The second level of personalised dietary advice will includ...