abstract background: it is well recognized that different patients respond in different ways to medications. the inter-individual variations are greater than the intera- individual variations, a finding consistent with the notion that inheritance is a determinant of drug responses. the recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the h...

background: plasmodium vivax malaria accounts for approximately 88% of malaria cases in iran. there is limited in­formation on genetic diversity of p. vivax in the country and a need to develop and apply an effective vaccine against the dis­ease is necessary. among many potential candidates, msp -3β gene is promising target. this study was designed and car­ried out to determine the variation of...

inter simple sequence repeat (issr) analysis was performed to evaluate genetic diversity and genetic structure of six capoeta trutta populations from two main watersheds in the kurdistan province. fish samples were caught from the choman, shooei, garmab rivers in the choman watershed and from the gheshlagh, gavarood, sirvan rivers in the sirvan watershed. from six used dinucleotide primers, thr...

A study was undertaken to evaluate the genetic variation in the 10th generation of a breeder flock of native breed selected for high egg and meat production in native fowls breeding station, Mazandaran, Iran. Venous blood samples were collected from 100 birds of both sexes. The RAPD-PCR technique was applied to generate a DNA fingerprint of individuals. Initially, a total of 20 ten-nucleotide a...

Copyright: © 2015 Razdan A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. GlobalFilerTM Express PCR Amplification Kit is a highly discriminative STR kit developed by Life Technologies to meet the requ...

we estimated the genetic diversity and population structure of persian sturgeon across six regions of caspian sea along the coast of iran using eight dna microsatellite loci. full genotypes were obtained for 195 individuals of persian sturgeon. significant differences were detected between a. persicus specimens collected from sefidrud river (p≤0.0001) and those collected from the southern fishe...

kutum is considered as one of the anadramous species of the caspian sea. due to continuous population decline of the fish since 1975, iranian fisheries organization started to restock this species. nowadays, there is growing concern over the effects of restocking on natural populations. for this purpose, population structure and genetic variation of this species in the iranian coastline of casp...

In the wake of seminal work by Dobzhansky and Muller, hybrid dysfunction is usually attributed to incompatible mutations in different genes arising in different populations. This Dobzhansky-Muller (D-M) model is among the most important contributions of theoretical population genetics. Here I make formal connections between the D-M model and the quantitative genetic interpretation of hybrid dys...

Population genetic structure of stellate sturgeon (Acipenser stellatus) in 197 adult specimens from four fishery regions along the Iranian coastline of the southern Caspian Sea was investigated using microsatellite markers. Out of 15 microsatellite primers, 11 loci were produced, in which 10 of them were polymorphic and 1 was monomorph. Totally, 184 alleles were identified and on average 13.1 a...