conclusions our results show a significant association of nos3 and mthfr gene polymorphisms with coronary atherosclerotic lesions. therefore, these variants might influence the risk of coronary artery disease, specifically in the iranian population. results we specifically detected the nos3 tt genotype in 12 patients (11.11%) and did not find the same genotype in any of the controls. the freque...

in recent years, the relationship between insertion and deletion (indel) polymorphisms in promoter region (23 bp) and intron 1 (12 bp) of prnp gene (prion protein coding gene) and their relationship to susceptibility of classical bovine spongiform encephalopathy (bse) have been reported. insertions of these two polymorphisms increase resistance to classical bse, while the deletions of these two...

Background: Type 2 diabetes mellitus that characterized by insulin resistance and it is a risk of many diseases the impact genetic factors on well documented. Vitamin D receptor (VDR) gene polymorphisms have been linked to T2DM. In this study, we analyzed relation between TaqI ApaI VDR T2DM subjects using PCR-RFLP method in Kurdish patients.

ABSTRACTTuberculosis is an infectious disease which occurs widely in the world and becomes one of the top 10 causes of death worldwide. Mutations of the RpoB gene cause the resistance of Mycobacterium tuberculosis to rifampicin that contributes to the occurrence of MDR-TB. This study aimed to determine the pattern of rpoB gene polymorphisms in the MDR M. tuberculosis in Semarang, Indonesia. Mos...

This article shows the results of studies in course which a comparative aspect LEP polymorphism was studied subpopulations Holstein dairy cattle cows with fatty hepatosis and healthy animals. is first time such are being conducted. In this case, hepothesis about relationship genetic markers, particular leptin gene, risk developing progression liver disease model when determining frequency occur...

aim : the propose of this study was to evaluate the probable correlation between exon and intron polymorphisms of p53 gene and their association with clinicopathological aspects of gastritis. background : regarding to the decisive role of p53 in the development of a variety of human cancers, a comprehensive study concerning probable correlation between polymorphisms in the p53 intron and exon i...

Background: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the peripheral blood of PE patients have been reported. Several single nucleotide polymorphisms (SNP) within ...

Despite improving cure rates in childhood acute lymphoblastic leukemia (ALL), therapeutic side effects and relapse are ongoing challenges. These can also affect the central nervous system (CNS). Our aim was to identify germline gene polymorphisms that influence risk of CNS events. Sixty single nucleotide (SNPs) 20 genes were genotyped a Hungarian non-matched ALL cohort 36 cases with chemotherap...