نتایج جستجو برای: gastroprotective action
تعداد نتایج: 611964 فیلتر نتایج به سال:
The present study was performed to evaluate the gastroprotective activity of Schiff base ligand derived from the condensation reaction of tryptamine (an indole derivative) and 5-nitrosalicylaldehyde (TNS) and its nickel (II) complex against ethanol-induced gastric ulcer in rats. The compounds were orally administered with low (30 mg/kg) and high (60 mg/kg) doses to ulcer-induced Sprague-Dawley ...
Purpose WIN-34B is a butanol fraction extract from the mixture of two oriental herbs, the dried Lonicera japonica flowers and the root of Anemarrhena asphodeloides. In previous studies, we indentified that WIN-34B has analgesic, anti-inflammatory, gastroprotective and safety effects. In this study, we measured the major components and investigated the efficacy of WIN-34B on cartilage protection...
OBJECTIVES The antiulcer activity of Benincasa hispida (Thunb.) Cogn. fruit was evaluated in rats against ethanol-induced gastric mucosal damage, pylorus ligated (PL) gastric ulcers, and cold restraint-stress (CRS)-induced gastric ulcer models. METHODS Petroleum ether and methanol extracts were administrated orally at the dose of 300 mg/kg, and omeprazole (reference standard) at the dose of 2...
New diterpenylquinones, combining a diterpene diacid and a naphthoquinone, were prepared from junicedric acid and lapachol. The new derivatives were assessed as gastroprotective agents by the HCl-EtOH-induced gastric lesions model in mice as well as for basal cytotoxicity on the following human cell lines: Normal lung fibroblasts (MRC-5), gastric epithelial adenocarcinoma (AGS), and hepatocellu...
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