Background. This study addresses clinicopathological differences between patients with gastric cardia and subcardial cancer with and without esophagogastric junctional invasion. Methods. We performed a single-center, retrospective cohort study. We studied patients who underwent curative surgery for gastric cardia and subcardial cancers. Tumors centered in the proximal 5 cm of the stomach were c...

CD147 (also named as Basigin or EMMPRIN) might promote cancer invasion and metastasis by inducing MMP and VEGF synthesis in tumor microenvironment. We performed a systematic meta and bioinformatics analysis through multiple online databases up to March 14, 2017. Up-regulated CD147 expression was found in gastric cancer, compared with normal mucosa (p < 0.05). The male patients with gastric canc...

Etiology Many risk factors have been associated with the development of gastric cancer, and the pathogenesis is most likely multifactorial (Table 1).2,5,6 Although significant, genetic abnormalities (such as DNA aneuploidy, oncogene amplification or mutation, and allelic loss of tumor suppressor genes) are not understood well enough to allow formulation of a sequence of progression to the devel...

The aim of this study was to investigate the effect and mechanism of Helicobacter pylori infection in the invasion and metastasis of gastric cancer. Specimens from 80 patients with gastric cancer (of which 20 patients had metastatic gastric cancer) and 40 patients with chronic gastritis were included in this study. H. pylori infection was determined by ELISA and the expression of matrix metallo...

BACKGROUND In a recent study, it was reported that transcatheter arterial embolization with spherical embolic material for life-threatening hemorrhages in various cancer patients was safe and effective. Calibrated microspheres are able to access distal regions of the target arteries, which results in the disappearance of tumor staining. However, there are few reports on the pathological behavio...

Abstract Laparoscopic adjustable gastric banding (LAGB) is a widely accepted and effective bariatric procedure. Gastric cancer following surgery uncommon, with only few occurrences reported. There are nine incidences of adenocarcinoma after recorded in the literature. Squamous cell carcinoma (SCC) by comparison, encountered far less overall stomach malignancies. We describe case 69-year-old wom...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

BACKGROUND In gastric cancer, the current AJCC numeric-based lymph node staging does not provide information on the anatomical extent of the disease and lymphadenectomy. A new anatomical location-based node staging, proposed by Choi, has shown better prognostic performance, thus soliciting Western world validation. STUDY DESIGN Data from 284 gastric cancers undergoing radical surgery at the S...