Single-distilled water encapsulated in graphene pockets has been studied by aberration-corrected high-resolution transmission electron microscopy and electron energy loss spectroscopy at an acceleration voltage of 80 kV. Inside the graphene pockets, crystallization and in situ crystal growth are reported and identified as the insoluble AII phase of CaSO4 (anhydrite) in a quasi-two-dimensional s...

OBJECTIVE This study is a proof of concept to determine the efficacy of a custom-fabricated tray in placing antimicrobial and debriding agents in the periodontal pockets of persons with active gingival infections. Localized subgingival delivery of antimicrobial and antibiotic agents is routinely employed as adjunctive therapy for the treatment and management ofperiopathogens associated with per...

A study was conducted to examine the effect of endotoxin present in periodontal pockets on the proliferation and attachment of human cell lines on the culture plates (Ca9-22 and gingival fibroblasts). The endotoxin was collected from periodontal pockets of anterior teeth in patients with periodontal disease by subgingival irrigation with sterilized distilled water. The solutions obtained were t...

γ-secretase is responsible for the proteolysis of amyloid precursor protein (APP) into short, aggregation-prone amyloid-beta (Aβ) peptides, which are centrally implicated in the pathogenesis of Alzheimer's disease (AD). Despite considerable interest in developing γ-secretase targeting therapeutics for the treatment of AD, the precise mechanism by which γ-secretase produces Aβ has remained elusi...

The dynamic nature of protein structures provides challenges and opportunities for ligand design. I will first discuss some of the different ways in which protein dynamics can be targeted, giving examples from our experience in the design of inhibitors of thymidylate synthase [1-3]. I will then describe the development of a computational toolbox (TRAPP: TRAnsient Pockets in Proteins) to identif...

Because current remote monitor systems can’t deal with problems of real-time transmissions in the bad condition of network very well, this article presents a study which is combined with the evaluation of video streams, adjustment and sealing user-defined data pockets and discarding useless data pockets. The goal of this solution is to transmit video information of national grain depot. And its...

Background: PfEBA-140 recognizes sialic acid on its receptor Glycophorin C during erythrocyte invasion. Results: PfEBA-140 contains two sialic acid binding pockets distinct from other sialic acid binding proteins and with divergent roles in receptor recognition. Conclusion: The glycan binding pockets define receptor recognition, specificity, and putative switching. Significance: The first detai...

Methane is the most important greenhouse gas after carbon dioxide, with particular influence on near-term climate change. It poses increasing risk in the future from both direct anthropogenic sources and potential rapid release from the Arctic. A range of mitigation (emissions control) technologies have been developed for anthropogenic sources that can be developed for further application, incl...

The mid-1998 troubles between India and Pakistan are used to demonstrate that a realvalued Genetic Algorithm (GA) can find workable solutions to Richardson’s Theory of Arms Races. This theory, developed in the late 1940s, needs such a big search space that it was never very useful — until the arrival of GAs. Rough ‘starter’ values for the rate-constants in Richardson’s equations are gleaned fro...

This paper deals with secondary cooling in a continuous caster. In particular, it inhomogeneity caused by spray arrangement and segmented rolls used for leading the strand. The section is placed under mold. Segmented are supported bearings several places across Sprayed water can flow gaps between where bearing pocket located. main question that was experimentally studied how this geometry influ...