نتایج جستجو برای: gambogic acid
تعداد نتایج: 747447 فیلتر نتایج به سال:
The transcription factor, STAT3, is associated with proliferation, survival, and metastasis of cancer cells. We investigated whether gambogic acid (GA), a xanthone derived from the resin of traditional Chinese medicine, Garcinia hanburyi (mangosteen), can regulate the STAT3 pathway, leading to suppression of growth and sensitization of cancer cells. We found that GA induced apoptosis in human m...
As a good photosensitizer, TiO₂ nanomaterials show potential biomedical applications, such as drug carriers or enhancers in photodynamic therapy. In this contribution, novel nanocomposites through the blending of TiO₂ nanofibers with the active compound, gambogic acid (GA), were explored, and the results showed that GA could inhibit cancer cell proliferation in a time-dependent and dose-depende...
To minimize the side effects and the multidrug resistance (MDR) arising from daunorubicin (DNR) treatment of malignant lymphoma, a chemotherapy formulation of cysteamine-modified cadmium tellurium (Cys-CdTe) quantum dots coloaded with DNR and gambogic acid (GA) nanoparticles (DNR-GA-Cys-CdTe NPs) was developed. The physical property, drug-loading efficiency and drug release behavior of these DN...
In multiple myeloma (MM), the hypoxic environment is an important factor causing tumor angiogenesis, which is strongly correlated to disease progression and unfavorable outcome by activating the key transcription factor, hypoxia-inducible factor-1α (HIF-1α). Gambogic acid (GA) is the major active ingredient of gamboge, which has been shown to possess antitumor effect by in vitro and in vivo stu...
گیاهان juniperus excelsa m.beib. ,juniperus communis l. و juniperus sabina l. از گونههای دارویی با ارزش و معطر متعلق به جنس سروکوهی و راسته مخروطیان میباشند که در ارتفاعات رشته کوه البرز پراکندگی دارند. هدف از این پژوهش، شناسایی و مقایسه اجزای تشکیل دهنده اسانس میوه ها و سرشاخههای هوایی این گیاهان میباشد. در این تحقیق میوه و سرشاخههای سه گونه فوق در مرداد سال 1390 از منطقه هزار جریب بهشهر...
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