Contrast-enhanced MRI lymphography shows potential to identify alterations in lymph drainage through lymph nodes (LNs) in cancer and other diseases. MRI studies have typically used low molecular weight gadolinium contrast agents, however larger gadolinium-loaded nanoparticles possess characteristics that could improve the specificity and sensitivity of lymphography. The performance of three gad...

BACKGROUND AND PURPOSE Inflammatory multiple sclerosis (MS) lesions are characterized by microglia activation and infiltration of T cells, B cells, and macrophages across the blood-brain barrier (BBB). In the experimental autoimmune encephalomyelitis (EAE) rat model of MS, previous MR imaging investigations with a new contrast agent ultra-small-particle iron oxide (USPIO) that accumulates in ph...

Nephrogenic systemic fibrosis, initially called nephrogenic fibrosing dermopathy, has been strongly linked to exposure to gadolinium-based contrast media used in magnetic resonance imaging in patients with renal insufficiency. This review discusses recent advances in our understanding of the pathophysiology and clinical approach to patients with chronic kidney disease who require diagnostic ima...

Abstract Herein, we present a detailed study of the structural, optical, and electrochemical responses Gd 2 O 3 doped with nickel zinc ferrite nanoparticles. Doping Ni 0.5 Zn Fe 4 nanoparticles to powder was done through thermal decomposition at 1000 °C. The average grain size mixture determined be approximately 95 nm, phases cubic , GdO, orthorhombic prisms GdFeO were identified. focused ion b...

OBJECTIVE To evaluate the multiphase contrast-enhanced magnetic resonance (MR) imaging features of Bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis (GP). MATERIALS AND METHODS Magnetic resonance images obtained from five patients with histopathologically proven BCG-induced GP were retrospectively analyzed for tumor location, size, signal intensity on T2-weighted images (T2WI) ...

Objective. Evaluate the incidence of nephrogenic systemic fibrosis (NSF) in patients with liver disease in the peritransplant period. Materials and Methods. This IRB approved study retrospectively reviewed patients requiring transplantation for cirrhosis, hepatocellular carcinoma (HCC), or both from 2003 to 2013. Records were reviewed identifying those having gadolinium enhanced MRI within 1 ye...

STUDY OBJECTIVE To review the published experience with gadolinium-enhanced magnetic resonance angiography (MRA) for the detection of acute pulmonary embolism (PE) in order to test the hypothesis that gadolinium-enhanced MRA may be potentially sensitive and specific enough to include it among diagnostic alternatives in the evaluation of patients with suspected PE. METHODS Studies were identif...

INTRODUCTION Nephrogenic systemic fibrosis is a condition that has recently been recognized in patients with chronic renal disease and is associated with use of gadolinium-based contrast agents of ubiquitous use in magnetic resonance imaging scans. The condition is believed to arise through inadequate renal clearance of the gadolinium-based contrast agents, resulting in bodily deposition of the...

In 2001, Bernstein, West and Gupta [i] described a possible campaign to monitor nuclear fission reactions over large distances using arrays of Super-Kamiokande (SuperK) type water Cherenkov detectors, modified to include neutron-capture elements such as gadolinium. This modification would allow sensitivity to reactor and other low energy antineutrinos through the inverse beta decay interaction....

The formation and physico-chemical properties of biomaterial, based on double-stranded (ds) DNA molecules and bearing high concentration of gadolinium, is described. This “rigid” biomaterial demonstrate a few unique properties: 1) the ds DNA molecules forming complexes with gadolinium are fixed in the spatial structure of “rigid” particles, 2) an abnormal negative band in the circular dichroism...