T lymphocytes that are activated in the autologous mixed lymphocyte reaction (MLR) have suppressor activity. Concanavalin A (Con A) augments the suppressor activity generated in cultures containing both T and non-T lymphocytes and can induce suppressor activity in T-lymphocyte preparations that contain too few (10%) non-T cells to generate a significant autologous MLR. However, when such T-lymp...

We examine the class of multi-linear representations (MLR) for expressing probability distributions over discrete variables. Recently, MLRs have been considered as intermediate representations that facilitate inference in distributions represented as graphical models. We show that MLR is an expressive representation of discrete distributions and can be used to concisely represent classes of dis...

Lymphocyte proliferation in vitro may follow antigen recognition and serve as a correlate of cell-mediated immunity. Lymphocyte proliferation can also be simulated by nonimmune mechanisms as, for example, following culture with plant lectin, lipopolysaccharides, or staphylococcal protein A (1). The autologous mixed lymphocyte reaction (MLR) refers to the proliferation of T lymphocytes cultured ...

Leucocyte Alkaline Phosphatase Activity (LAPA) in normal healthy individuals was lound to be in the range 17-110. It was markedly increased in patients with myeloid leukemoid reaction (MLR) in the range 100-220. However it was decreased in patients with chronic myeloid leukaemia (CML) in the range 0-16. Increased LAPA in MLR is indicative of enhanced digestive capability of neutrophils while de...

Gene Expression Programming (GEP) is a novel genetic algorithm, a highly effective, stable random searching method. We take GEP to make models of Quantitative Structure-Retention Relationship (QSRR) for a series of oxygen-containing organic compounds of GC retention index, and compare the predictive results with Artificial Neural Network (ANN) and Multiple Linear Regression (MLR). The correlati...

Predicting the stream flow is one of the most important steps in the water resources management. Artificial neural network (ANN) has been suggested and applied for this purpose by many of researchers. In such studies for verification and comparison of ANN results usually the popular methods such as multivariate linear regression (MLR) is used. Unfortunately, the presented methodology in some re...

The intestinal lymph pathway plays an important role in the pathogenesis of organ injury following superior mesenteric artery occlusion (SMAO) shock. We hypothesized that mesenteric lymph reperfusion (MLR) is a major cause of spleen injury after SMAO shock. To test this hypothesis, SMAO shock was induced in Wistar rats by clamping the superior mesenteric artery (SMA) for 1 h, followed by reperf...

In the guinea pig and gerbil, individual components within the MLR time frame differ in optimal recording location. Specifically, MLR components obtained from the midline differ from those obtained over the temporal lobe. In the present paper midline and temporal lobe components were shown to differ not only in scalp topography but also in response to the following experimental manipulations: i...

OBJECTIVE The aim of this study was to compare the pharmacodynamics of a new multilayer-release (MLR) formulation methylphenidate (MPH; Biphentin) with immediate-release (IR) MPH (Ritalin) in a double-blind, cross-over, placebo-controlled study in patients with attention-deficit/hyperactivity disorder (ADHD). METHOD Patients were randomized to equivalent doses of MPH as MLR (once per day), IR...