BACKGROUND Mycotic keratitis by moulds (MKM) is an important cause for corneal blindness and usually carries an unfavorable prognosis. AIMS This study describes the risk factors and demographic and microbiological features of all MKM cases in Santa Lucía Ophthalmology Hospital during a period of 6 years. METHODS A prospective study was performed for all MKM cases diagnosed between October 2...

We present a case of infectious crystalline keratopathy in a patient with Graft-versus-Host disease (GVHD) who developed satellite fungal keratitis. A 51-year-old man was referred for bilateral total persistent corneal epithelial defects with severe dry eye. Although persistent epithelial defect healed with medical therapy, he developed stromal keratitis with satellite lesions confirmed to be s...

INTRODUCTION This study was conducted to determine the epidemiological pattern and risk factors associated with corneal ulcers in rural areas of western Maharashtra, India, and to identify the bacterial and fungal agents responsible for causing keratitis. METHODS A total of 852 patients with corneal ulceration were included in the study. Sociodemographic data and information pertaining to ris...

Introduction Contact lens wearing has been increased globally during recent decades, which is one of the main risk factors for developing microbial keratitis. Microbial keratitis a severe and dangerous condition that causes cornea inflammation. It can lead to corneal scarring perforation or even endophthalmitis visual loss if it remains untreated. Among bacterial, fungal, protozoal, viral agent...

BACKGROUND In Singapore, an outbreak of fungal keratitis caused by members of the Fusarium solani species complex (FSSC) was identified in March 2005 to May 2006 involving 66 patients. Epidemiological investigations have indicated that improper contact lens wear and the use of specific contact lens solutions were risk factors. METHODS We assessed the genetic diversity of the isolates using AF...

Background: Fungal keratitis (keratomycosis) is the inflammation of the eye's cornea that results from fungal infection. Case Report: A 29-yrs-old female patient who wears contact lenses presented with ocular pain, redness and blurred vision. Following failures with previous antibacterial topical treatment, a corneal scraping was sent to the mycology laboratory. Fungal elements have been demons...

Background: Suppurative keratitis is a common ophthalmic condition mostly caused by fungi. Apart from fungal culture, wet preparation using 10% Potassium hydroxide (KOH) for microscopic detection of fungal elements is a rapid and accurate method of laboratory diagnosis. Purpose: This prospective and cross sectional study was undertaken in order to evaluate the diagnostic sensitivity of wet prep...

Background: Fungal keratitis is often difficult to eradicate and requires long treatment. Antifungal agents have lower efficacy because of low tissue penetration the indolent nature infection. Fluconazole has effective ocular ability, reaching aqueous concentration as same plasm concentration. Multilayer amniotic membrane transplantation (MLAMT) been shown be a promising surgical procedure reco...

PURPOSE Innate immunity had been thought to be critical in the pathogenesis and prognosis of fungal keratitis. This study was conducted to determine whether experimental Candida albicans keratitis (CaK) induces an adaptive immune response. METHODS Experimental murine CaK was induced by intrastromal injection of C. albicans spores, and fungal pneumonia was induced by intranasal inhalation of s...