BACKGROUND AND PURPOSE Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. This disorder results in recurrent life-threatening bacterial and fungal infections. Aspergillus species are the most common fungal infections in these patients. CASE REPORT Herein, we present a case of fungal infection in a girl with ...

Article history: Received on: 06/07/2016 Revised on: 11/09/2016 Accepted on: 24/10/2016 Available online: 29/11/2016 Introduction: Fungal infections have risen exponentially and are a cause of significant morbidity and mortality in Intensive Care Unit. The study was done to assess the prevalence of fungal pathogens in ICU patients, their antifungal susceptibility profile and biofilm production....

The frequency of fungal etiology of sinusitis contains between 9 and 49 % according to different authors. Fungal rhinosinusitis has been divided into noninvasive and invasive forms. Noninvasive infections include fungus ball (mycetoma) and allergic fungal rhinosinusitis. Invasive infections include acute (or fulminates) fungal rhinosinusitis and invasive chronic rhinosinusitis. The case of chro...

background and purpose: detection of agents responsible for cutaneous mycosis may be effective in the prevention of fungal infections from environmental and animal sources. with this background in mind, in this study, we aimed to identify the distribution of cutaneous mycotic infections in patients referred to imam reza hospital of mashhad, iran during 2000- 2011. materials and methods: in tota...

Pulmonologists and intensivists often care for patients at risk for infections caused by both Aspergillus and Candida. Infection with either can lead to severe life-threatening disease, particularly in immunosuppressed patients, with mortality rates for invasive fungal disease often exceeding 30%. For both organisms, multiple diagnostic challenges remain while newer diagnostic modalities are be...

Invasive fungal rhinosinusitis is a potentially fatal infection that affects immunocompromised patients. Prognosis is generally poor despite aggressive medical and surgical treatments. We present the first reported case of invasive fungal sinusitis in a healthy 18-year-old male athlete who was taking anabolic androgenic steroids (AAS). The effects of excessive AAS use on the immune system are n...

Fungal infections pose a significant global health burden, affecting millions of individuals each year. Conventional antifungal therapies often suffer from limitations such as drug resistance and adverse side effects. As result, researchers have turned their attention to natural remedies, particularly medicinal plants, in search novel agents. This review article aims provide an up-to-date detai...

Despite the introduction of new antifungal agents, resistances to antifungal therapy continue to increase and outcome of invasive fungal infections treatment is frequently suboptimal. A large amount of the recent effort in antifungal drug discovery has focused on a limited set of targets with functions known or expected to be important for fungal viability and virulence. A variety of techniques...

we present a case of allergic fungal sinusitis (afb) in a 20-year old man with few months' history of bilateral nasal obstruction and discharge with unilateral proptosis that underwent maxillary antrostomy due to the mass in paranasal sinuses. histological examination of tissue showed branching fungal hyphae interspersed with allergic mucin without fungal invasion to soft tissue. the patient re...

Invasive fungal infections have increased in importance, largely because of the increasing size of the population at risk. Candida species remain the fourth most important cause of hospital-acquired bloodstream infections. Infections with Candida species other than C. albicans appear to have become more common, but significant geographic variation has been reported. Invasive aspergillosis and o...