BACKGROUND The gonadotropins (GtHs), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are produced in the pituitary gland and regulates gametogenesis through production of gonadal steroids. However, respective roles of two GtHs in the teleosts are still incompletely characterized due to technical difficulties in the purification of native GtHs. METHODS Native FSH and LH were pu...

Role of the bed nucleus of stria terminalis (BST) in the control of gonadotropin release in the female rat was studied. Electrical stimulation of the BST on the day of diestrus II increased the serum concentration of FSH, but not of LH. The stimulation on the day of estrus increased serum concentration of LH as well as on the day of proestrus. In the ovariectomized and estrogen-treated rat, the...

LH, FSH and testosterone variations were compared during the prepubertal period in Romanov and Ile-de-France ram lambs born in the spring. Mean plasma LH levels increased significantly between the 1st and 8th week of age in the Romanov and between the 1st and 12th week of age in the Ile-de-France. At 1 month of age, the number of LH and testosterone pulses per hour was higher in Romanov than in...

BACKGROUND The use of mixed or blended protocols, that utilize both FSH and hMG, for controlled ovarian hyperstimulation is increasing in use. To reduce the number of injections a patient must administer, many physicians instruct their patients to mix their FSH and hMG together to be given as a single injection. Therefore, the goal of this study was to definitively determine if the FSH and LH b...

The effects of various chemical and enzymatic treatments on the biological activity of porcine luteinizing hormone-releasing hormone (LH-RH) are described. This experiment was performed before the elucidation of the structure of LH-RH. LH-RH activity was abolished by the following endopeptidases: chymotrypsin, subtilisin, papain, and thermolysin, but not by pepsin or trypsin. Exopeptidases d...

Background: Gonadptropins are main regulator of women menstrual cycles during which ovulation occur. infertile women with high level of FSH are poor responder to ovulation during ART cycles and do not take good result. this Study is done to evaluate the effects of day three FSH and LH level on number and quality of fertilized oocytes in infertile women candidate for ART cycle. Based on this stu...

Follicular development is associated with both proliferation and differentiation of granulosa cells under the control of FSH. We show that regulation of genes involved in cellular proliferation by FSH can be functionally separated from the regulation of genes involved in granulosa cell differentiation by synergistic actions of activin and T. Incubation of undifferentiated rat granulosa cells wi...

Due to the stimulatory action of serotonin (5HT) and nitric oxide (NO) on the secretion of gonadotropins and PRL, this work aimed at investigating the participation of serotoninergic receptors 5HT(1) and 5HT(2) of the medial preoptic area (MPOA) in the control of luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin (PRL) secretion and the possible modulation by ovarian ste...

Purpose: This study aimed to evaluate the level of progesterone and progesterone-induced blocking factor (PIBF), an immune mediator, in non-obese patients with polycystic ovary syndrome (PCOS).
 Materials Methods: Totally 72 were recruited into divided 2 groups: The first group was diagnosed PCOS (n = 36) second healthy control (n=36). diagnosis made according Rotterdam diagnostic criteria...

The specific roles of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in controlling human spermatogenesis are poorly understood. We studied the effect of an experimentally induced, selective LH deficiency on sperm production in normal men. After a 3-mo control period, five men received 200 mg testosterone enanthate (T) i.m./wk to suppress LH, FSH, and sperm counts. Then, while ...