In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of hepatotoxicity, which was induced by carbon tet...

Objective: The present study was conducted to investigate antibacterial properties of fruit and flower of Peganum harmala. Material and Methods: Column chromatography, followed by preparative thin layer chromatography (TLC) was used for final purification. The structure of pure alkaloids was determined using spectroscopic methods (1H-N...

conclusions this investigation revealed that berberis fruit extract has beneficial metabolic effects in patients with type ii diabetes. barberry may improve glucose catabolism via glycolysis pathway, stimulate insulin secretion or improve insulin function and finally decrease glucose uptake. our results indicated that berberis fruit regulates glucose metabolism in patients with type 2 diabetes....

Objective: The aim was to evaluate cardioprotective activity of aqueous extract of Garcinia indica Linn fruit rinds. Methods: Wistar rats were divided into different groups. Two doses 250 mg/kg and 500 mg/kg b.w, p.o of the G. indica fruit rind extract (GIFE) were subjected for the evaluation of cardioprotective activity against isoproterenol (ISO) and ischemia reperfusion injury (IRI) induced ...

The present study was aimed to evaluate anthelmintic activity of aqueous and methanolic extract of Trapa natans L.var. bispinosa Roxb fruit peels and root. The plant commonly known as “Water Chestnut” in India and is an annual aquatic floating herb occurring throughout the Indian subcontinent and used traditionally for several medicinal purposes. The effect of this plant was evaluated for anthe...

Antioxidant activity of Feijoa sellowiana leaves and fruit peels was investigated employing various in vitro assay systems. IC50 for DPPH radical-scavenging activity was in the order: leaf aqueous extract, LW (7.25 ± 0.31) > leaf methanolic extract, LM (12.5 ± 0.34) > fruit peels aqueous extract, FW (20.25 ± 0.52) > fruit peels methanolic extract, FM (34.5.29 ± 0.44) μg ml, respectively. The ex...

Durian (Durio zibethinus murr.) and rambutan (Nephelium lappaceum) are popular exotic fruits grown and consumed in Southeast Asia. Two economically important cultivars of durian and rambutan were studied to assess their antioxidant and anti-inflammatory activities. Nondifferentiated U937 monocyte-like cells were pre-treated with non-toxic doses of ethanol extract from fruit pulp prior to induci...

Passion fruit seed was refluxed in methanolic water and further liquid - liquid extracted yielding n-Hexane, Ethyl acetate (EtOAc) and aqueous (Aq.) extracts. The EtOAc part was the most potent antioxidant (IC 50DPPH = 2.7 ± 0.2 and IC 50ABTS = 9.0 ± 0.0 µg/mL) that significantly (p < 0.05) better than Aq. extract (IC 50DPPH = 177.8 ± 1.3 and IC 50ABTS = 15.4 ± 0.0 µg/mL). The antioxidant EtOAc...

BACKGROUND & OBJECTIVES The study evaluated the hypolipidaemic and hepatoprotective effects of unripe Psidium guajava fruit peel aqueous extract in streptozotocin (STZ) induced severely diabetic rats by assaying their triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL) cholesterol, alkaline phosphatase (ALKP), asperate amino transeferase (AST), alanine amino transferase (A...

STUDY OBJECTIVE To evaluate the hemodynamic and electrocardiographic effects of a single dose of commercially available bitter-orange dried-fruit extract, which is increasingly being used in dietary supplements. DESIGN Randomized, double-blind, placebo-controlled, crossover study. SETTING University of Connecticut, Storrs Campus. SUBJECTS Eighteen healthy volunteers aged 18 years or older...