A typical air disc brake generates the braking torque by friction between rotor and pads located on both sides of rotor. Friction causes pad to wear every time brakes are applied. As a result, gap called running clearance is created Automatic adjuster compensates for keep stable. If any malfunction occurs in automatic adjuster, will not self-adjust get larger. In this study, effect clearances p...

In order to elucidate the physiological significance of plasma dopamine, blood pressure, pulse rate (PR), plasma concentrations of free or conjugated dopamine (free or conjugated pDA), noradrenaline (pNA) and adrenaline (pAd) were measured in 9 healthy volunteers. Blood sampling for the measurements was performed at a basal condition maintaining a supine position for 60 minutes, after twenty mi...

Postnatal administration of phencyclidine (PCP) in rodents causes major disturbances to neurological processes resulting in severe modifications to normal behavioral traits into adulthood. It is routinely used to model psychiatric disorders such as schizophrenia, producing many of the dysfunctional processes in the brain that are present in this devastating disorder, including elevated levels o...

LINGO-1 is a component of the tripartite receptor complexes, which act as a convergent mediator of the intracellular signaling in response to myelin-associated inhibitors and lead to collapse of growth cone and inhibition of neurite extension. Although the function of LINGO-1 has been intensively studied, its downstream signaling remains elusive. In the present study, a novel interaction betwee...

We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, ga...

Leucine-rich repeat and immunoglobulin domain-containing protein (Lingo-1) is a potent negative regulator of neuron and oligodendrocyte survival, neurite extension, axon regeneration, oligodendrocyte differentiation, axonal myelination and functional recovery; all processes highly implicated in numerous brain-related functions. Although playing a major role in developmental brain functions, the...

This study addressed warehouse storage location assignment problems (SLAP) to minimize total travelling distances in an order-picking process. The problem was formulated and presented as a mixed integer programming model. The LINGO optimization solver was then used to find solutions for a set of generated problems. The results showed that the LINGO optimization solver easily attained optimal so...

The objective of this study is to develop a new environmentally-friendly brake pad made from eggshells (Es) and banana peels (BPs) as reinforcement agents. E BP particles dual with various compositions were combined. E/BP mixture was then embedded on polymer matrix composing resin/hardener in 1:1 ratio. As standard, pads using single also fabricated. Physical properties (i.e. particle size, sur...