Block-face imaging is a scanning electron microscopic technique which enables easier acquisition of serial ultrastructural images directly from the surface of resin-embedded biological samples with a similar quality to transmission electron micrographs. In the present study, we analyzed the three-dimensional architecture of podocytes using serial block-face imaging. It was previously believed t...

INTRODUCTION Diabetes mellitus (DM) is one of the most common endocrine disease of modern life. Diabetic foot (DF) is the term for a foot of a patient suffering from DM with the potential risk of a number of pathological sequels, including infection, ulceration and/or destruction of deep tissue. GOAL To determine the importance of preventive measures to prevent the development of diabetic foo...

BACKGROUND Diabetic foot is a serious condition in patients with a long lasting diabetes mellitus. Diabetic foot treated improperly may lead not only to delayed ulceration healing, generalized inflammation, unnecessary surgical intervention, but also to the lower limb amputation. The aim of this study was to compare diabetic foot risk factors in population with type 2 diabetes and risk factors ...

Electron acceleration associated with various plasma kinetic instabilities in a nonrelativistic shock with very high Alfvén Mach number (M(A)~45) is revealed by means of a two-dimensional fully kinetic particle-in-cell simulation. Electromagnetic (ion Weibel) and electrostatic (ion-acoustic and Buneman) instabilities are strongly activated at the same time in different regions of the two-dimens...

A region of about 435 bases from the 5' noncoding region of foot-and-mouth disease virus RNA directs internal initiation of protein synthesis. This region, termed the internal ribosome entry site (IRES), is predicted to contain extensive secondary structure. Precise deletion of five predicted secondary structure features has been performed. The mutant IRES elements have been constructed into ve...

This study examined how duration of an unstressed final syllable in English is affected by conditions in the following word: stress (trochaic/iambic), accent (accented/unaccented), and initial stop voicing (voiced/voiceless). Results showed that the unstressed final syllable was shorter before an unstressed syllable, presumably due to polysyllabic shortening—i.e., the following unstressed sylla...

PURPOSE Medial longitudinal arch (MLA) strengthening has been considered an important part of successful flatfoot treatment. But, to date, the biomechanical loading behavior of the medial arch in flatfoot has not been evaluated. This study aimed to evaluate the MLA moment, MLA deformation angle, foot kinematics and ground reaction forces (GRF) in both normal foot and flatfoot groups. METHODS ...

A novel three-dimensional numerical model of the foot, incorporating, for the first time in the literature, realistic geometric and material properties of both skeletal and soft tissue components of the foot, was developed for biomechanical analysis of its structural behavior during gait. A system of experimental methods, integrating the optical Contact Pressure Display (CPD) method for plantar...

The aim of this work is to propose a new 2-DOF robotic platform with hybrid parallel-serial structure and to undertake its parametric design so that it can follow the whole range of ankle related foot movements. This robot can serve as a human ankle rehabilitation device. The existing ankle rehabilitation devices present typically one or more of the following shortcomings: redundancy, large siz...

Previous research has indicated that the H* of a nuclear accent may be realised as a flat stretch of contour rather than as a single turning point. The duration of this plateau and its alignment within the accented syllable and foot are affected by the segmental and prosodic structure of the utterance. The present work investigates whether a non-structural variable, namely pitch span, also affe...