the aim of this study was examination the relationship between mindfulness and drug craving in addicts undergoing methadone maintenance treatment.the subjects of this research were 80 addicts undergoing methadone maintenance treatment selected through available sampling from four addiction treatment center in ahvaz from march 2012 to september 2012. two questionnaires to examine the variables o...

OBJECTIVE Cocaine dependence is a major international public health concern. Its chronically relapsing nature is possibly related to craving intensity, which can be influenced by diverse biological and psychological aspects. This study aimed to evaluate the role of different personality traits in craving measured throughout a psychosocial treatment program. METHOD The sample comprised 66 coca...

OBJECTIVE To assess preliminarily the effectiveness of acamprosate in binge eating disorder (BED). METHOD In this 10-week, randomized, placebo-controlled, flexible dose trial, 40 outpatients with BED received acamprosate (N = 20) or placebo (N = 20). The primary outcome measure was binge eating episode frequency. RESULTS While acamprosate was not associated with a significantly greater rate...

Neurobiology, genetics and treatment of alcohol craving Alcohol craving has increasingly been considered an important issue in alcohol use disorders in the last decade. Biologic studies on alcohol craving were mainly focused on neurobiology, genetics and pharmacological treatment of this condition. In this report, we started from receptor systems, than we explained genetics and epigenetics of a...

Craving is an uncontrollable impulse to assume abusive substances, often associated with intense anxiety, dysphoria, irritability, agitation, impulsive or explosive behaviours, as well as with somatic symptoms such as headache and asthenia. Craving can be separated into two components: an ‘appetitive craving’, that is searching for the abusive substance as a source of pleasure, and an ‘aversive...

Craving is a key aspect of drug dependence that is thought to motivate continued drug use. Numerous brain regions have been associated with craving, suggesting that craving is mediated by a distributed brain network. Whether an increase in subjective craving is associated with enhanced interactions among brain regions was evaluated using resting state functional magnetic imaging (fMRI) in nicot...

Research on the mechanisms of craving often involves inducing craving in subjects in controlled settings. This article describes techniques that have been used to induce craving for alcohol, including (1) exposing subjects to actual alcoholic beverages, (2) exposing subjects to visual representations of alcoholic beverages, (3) manipulating the subjects' mood states, and (4) controlling environ...

Five experts respected for their work in the development of animal models of alcohol craving offer their perspectives in a roundtable discussion format. The panel members discuss the various definitions and theories of alcohol craving and the benefits and limitations of using animal models to study alcohol craving in humans. Animal models have helped further the understanding of craving by prov...