Spatial uncertainty caused by large-scale variation in fluoride (F?) occurrence remains a setback for water supply authorities the F? belts of world. It is estimated that approximately 80 million people East African Rift Valley (EARV) regions and volcanic areas exhibit wide variety fluorosis symptoms due to drinking with F? concentrations higher than 1.5 mg/L (WHO guideline limit). In this stud...

The territory of Poltava region belongs to the Buchatsky hydrogeological province, whose groundwater is characterized by an elevated fluorine level content. cause endemic dental fluorosis particularly in children’s population water consumption with surplus concentration this chemical element. Also, having a condition that develops from high fluoride drinking water- causes disorder hard tooth ti...

OBJECTIVE This study explored the association between an Alu I polymorphism at position 1,377 of the calcitonin receptor (CTR) gene and endemic fluorosis. SUBJECTS AND METHODS A case-control study of 321 participants was conducted in regions with high fluorosis rates (Wushan and Fengjie counties) and those without high fluorosis rates (Yubei Qu county; termed nonfluorosis areas) in Chongqing,...

BACKGROUND Brick-tea type fluorosis is a public health concern in the north west area of China. The vitamin D receptor (VDR)-FokI polymorphism is considered to be a regulator of bone metabolism and calcium resorption. However, the association of VDR-FokI polymorphism with the risk of brick-tea type fluorosis has not been reported. MATERIALS AND METHODS A cross sectional, case control study wa...

Endemic fluorosis is a worldwide environmental problem due to excessive fluoride, commonly due to increased drinking water fluoride levels but sometimes due to other sources such as food with high fluoride content. In India, 21 of the 35 states are known to have health problems associated with fluoride toxicity. The present report is a case of a 50-year-old female who was seen with progressive ...

The levels of sialic acid and glycosaminoglycans were explored in the sera of rabbit and human subjects who ingested fluoride and had clinical manifestation of fluorosis. Changes observed in the level of these chemical constituents in sera possibly reflect changes occurring in calcified and noncalcified tissues due to fluoride intoxication. The ratio of sialic acid content vs glycosaminoglycans...

Dental fluorosis is the result of chronic endogenic intake of fluorides in amounts exceeding the optimal daily dose of 1 ppm In our country different mineral waters with high content of fluorine are on the market. As a result in numerous regions and settlements the cases of fluorosis with different degrees of seriousness have become more frequent in recent years. The aim of this study is to tes...

BACKGROUND Fluorosis is a condition resulting from excessive ingestion of fluoride during early childhood leading to the formation of defective enamel. The increased fluoride content is thought to result in a metabolic alteration of ameloblasts, which results in defective matrix, and improper calcification of teeth. MATERIALS AND METHODS A total of 6244 patients between the ages of 6yrs to 60...

There has been public concern about children's intellectual performance at high levels of fluoride exposure, but few studies provide data directly to the question of whether low fluoride exposure levels less than 3.0 mg/L in drinking water adversely associated with children's intelligence. In this survey, we investigated the effects of low fluoride exposure on children's intelligence and dental...