Little is known about the effect of fluorides on bacteria. In large concentrations inorganic and organic fluoride compounds inhibit growth. Fluorine is not known to be an essential trace element for bacteria, fungi, or algae. Recently Davis and Dubos (1947) have shown that fluoride inhibits the action of a lipase on "tween 80" in concentrations that do not affect the growth of Mycobacterium tub...

Lewis base catalysed 1,3-dipolar cycloaddition between α,β-unsaturated acyl fluorides and N-[(trimethylsilyl)methyl]amino ethers has been achieved using 1 mol% DMAP. Competition experiments and (19)F-NMR studies indicate that the cycloaddition occurs preferentially between the α,β-unsaturated acyl fluoride and the unstabilised azomethine ylide. In addition, an enantioselective variant, using ch...