A variety of evidence indicates that [3H]desipramine can label neuronal norepinephrine uptake sites in brain membranes. Pretreatment of rat cerebral cortical membranes with 0.3 M KCl increases the ratio of high affinity to low affinity saturable [3H]desipramine binding. With this improved tissue preparation, we have confirmed our earlier observation that the high affinity [3H]desipramine bindin...

This study examines the involvement of GTP-binding proteins (Gps) in the regulation of Na+/H+ exchange and Ca2+ influx, which are increased in vascular smooth muscle cells from spontaneously hypertensive rats. Gp activity was modulated by fluoride, GTPgammaS, GDPbetaS, and antisense oligodeoxynucleotides complementary to conserved regions of the alpha- and beta-subunits of Gps (alpha-comm and b...

In vivo enamel fluoride (F) uptake as a function of time after a single application of a new topical APF gel, MinuteGelTM (gel A) , was compared to a control APF gel, Nupro ® (gel B). The retained F in enamel after different post-treatment intervals also was assessed. Forty orthodontic patients aged 10-16 with four premolars scheduled for extraction were divided into two subgroups according to ...

objectives: this study aimed to assess the self-reported knowledge and attitude of dentists towards fluoride prescription. materials and methods: a questionnaire survey was conducted at the national annual dental congress in 2010 in tehran-iran. dentists’ level of knowledge about the preventive effects of systemic and topical administration of fluoride was assessed as well as their attitudes to...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 1. Physicochemical Properties of Sevoflurane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 1.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 1.2 Degradation at CO2 Absorbents . . . . . . . . . . . . . . . . . ...

background; fluoride is an essential nutrient for the human body. the major routes of fluoride intake include food and drinking water, though the absorption of fluoride from food is much easier. the aim of this study was to evaluate the amount of fluoride in the soil and tomato and onion crops on farms of zanjan. methods; three farms of each crop (tomato and onion) were selected randomly. each ...

The prevalence of dental fluorosis in the United States has increased during the last 30 years. In this study, we used a mathematical model commonly employed by the U.S. Environmental Protection Agency to estimate average daily intake of fluoride via all applicable exposure pathways contributing to fluorosis risk for infants and children living in hypothetical fluoridated and nonfluoridated com...

OBJECTIVES The influence of toothbrushing duration and dentifrice quantity on fluoride efficacy against dental caries is poorly understood. This study investigated effects of these two oral hygiene factors on enamel remineralisation (measured as surface microhardness recovery [SMHR]), enamel fluoride uptake (EFU), and net acid resistance (NAR) post-remineralisation in a randomized clinical stud...

Background and purpose: Fluoride is one of the drinking water contaminants regulated by EPA. This ion, in low doses in the mouth reduces tooth decay without health risk and at much higher doses causes health complications and can be toxic. The major sources of exposure to fluoride are drinking water, food, dental products, and pesticides. The biggest contributor to exposure for most people in I...