The most commonly used topical pharmacologic agents for symptomatic management of hemorrhoids include vasoconstrictors, astringents, anesthetics, keratolytics, corticosteroids, and antipruritic agents. Some of these drugs have been involved in contact dermatitis [1-7]. A 57-year-old woman presented with a pruritic, sharply demarcated, erythematous rash on the anogenital area that spread within ...

Topical foscarnet (PFA) and acyclovir (ACV) were compared in the dorsal cutaneous guinea pig model of herpes simplex virus type 1 infection. The relative order of efficacy was PFA cream greater than ACV cream greater than ACV ointment. In vitro studies demonstrated that PFA and ACV formulated in cream vehicles penetrated through guinea pig skin 7- to 10-fold faster than did ACV in ointment.

Extracts of Aloe vera whole plant, Eucalyptus globulus leaves, Ficus infectoria bark, Ficus religiosa bark and Piper betel leaves were studied for antibacterial activity on resistant and sensitive strains, isolated from skin and soft tissue infections. A combination of hot alcoholic extracts of Ficus infectoria, Ficus religiosa and Piper betel were found to be more effective against all the iso...

Shark (Carcharhinus sorrah) is a fish whose entire endoskeleton composed of cartilage. Fish cartilage widely used for treatment because shark (SC) contains glucosamine (GS) and chondroitin sulfate (CS) compounds. This study aims to determine the benefits derived from SC extract on lizard tail regeneration. The was initiated by testing characteristics ointment which included tests spreadability,...

BACKGROUND The chronic and relapsing nature of vulvar lichen sclerosus (VLS) represents a challenge for its long-term management after an effective treatment with topical corticosteroids. OBJECTIVES To assess the effectiveness of proactive, twice-weekly application of mometasone furoate 0·1% ointment, compared with daily topical vitamin E or cold cream, in keeping VLS in remission and reducin...