The "no reaction" lateral flow assay (nrLFA) uses a simplified LFA structure with no conjugate pad and no stored reagents. In the nrLFA, the capillary-based transport time or distance is the key indicator, rather than the outcome of a biochemical reaction. Hence, the calibration and reproducibility of the nrLFA device are critical. The capillary flow properties of several membrane types (nitroc...

A review of some recent advances focusing on the problem of nano-scale fluids far from equilibrium modelled by nonequilibrium molecular dynamics (NEMD) is presented. It will be demonstrated how novel materials such as dendrimers can be successfully modelled using NEMD methods and how the distortion of their geometry by the imposed field has a significant influence on the transport properties of...

Most microfluidic chips utilize off-chip hardware (syringe pumps, computer-controlled solenoid valves, pressure regulators, etc.) to control fluid flow on-chip. This expensive, bulky, and power-consuming hardware severely limits the utility of microfluidic instruments in resource-limited or point-of-care contexts, where the cost, size, and power consumption of the instrument must be limited. In...

Following recent works of several authors like Huilgol, Bhattacharya etd. and Javadpour et al., this paper is to contribute further to the literature of axial flow in a rotational coaxial rheometer. We consider axial flow of Herschel Bulkley mode1 between two concentric cylinders with the inner one rotating, while the outer cylinder is held stationary. An attempt has been made to direct the...

Numerical simulations of PTT fluids in axisymmetric sudden contractions were carried out to investigate the effect of contraction ratio on the flow patterns under conditions of negligible inertia. The PTT model selected has a linear stress coefficient, and contraction ratios (CR) in the range 4:1 to 100:1 were investigated. The simulations are based on a finite volume methodology using very fin...

Two types of laminar flows of non-Newtonian fluids in annuli with stationary outer cylinder are analysed from the viewpoint of existence of an exact analytical or almost exact analytical (quasisimilarity) solution relating volumetric flow rate and axial pressure gradient. The exact analytical solution is derived for the Vocadlo (RobertsonStiff) fluids when flow is caused simultaneously by the i...

This article addresses the issue of reproducing quantitative pressure-drop predictions for constant shear-viscosity fluids in contraction and contraction/expansion flow geometries. Experimental observations on pressure-drop for severe strain-hardening Boger fluids reveal significant enhancement above Newtonian fluids in axisymmetric but not planar configurations. This discrepancy has eluded pre...

Using the generalized variable formulation of the Euler equations of fluid dynamics, we develop a numerical method that is capable of simulating the flow of fluids with widely differing thermodynamic behavior: ideal and real gases can be treated with the same method as an incompressible fluid. The well-defined incompressible limit relies on using pressure primitive or entropy variables. In part...

During the past few decades molecular dynamics has been a widely applied tool to simulate fluid confined in micro/nano geometries. What makes interfacial fluids fundamentally different from the bulk fluid is the fact that their density varies considerably over microscopic distances. A class of such strongly inhomogeneous fluids are fluids confined in very narrow channels by solid boundaries. In...

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