In this paper we focus on model-based statistical signal processing and how some problems that are associated with it can be solved using fuzzy logic. We explain how uncertainty (which is prevalent in statistical signal processing applications) can be handled within the framework of fuzzy logic. Type-1 singleton and non-singleton fuzzy logic systems (FLSs) are reviewed. Type-2 FLSs, which are r...

We present deep u-, and g-band images taken with the MegaCam on the 3.6 m Canada-France-Hawaii Telescope (CFHT) to support the extragalactic component of the Spitzer First Look Survey (hereafter, FLS). In this paper we outline the observations, present source catalogs and characterize the completeness, reliability, astrometric accuracy and number counts of this dataset. In the central 1 deg2 re...

Knowledge of fog and low stratus (FLS) cloud patterns life cycles is important for traffic safety, the production solar energy analysis processes in climate system. While meteorological stations provide information on FLS, a data set describing FLS formation dissipation times large spatial temporal scales does not yet exist. In this study, we use logistic regression to extract from satellite-ba...

Objective: To investigate the development and clinical characteristics of flail leg syndrome (FLS) improve clinicians’ recognition ability disease. \quad Method：We reviewed data, electromyography, cerebrospinal fluid test, lumbar MRI a patient diagnosed with syndrome(FLS) in seventh Affiliated Hospital Sun Yat-sen University. Results: Clinical symptoms limited both lower limbs, including asymme...

OBJECTIVES Hypoxia-inducible factor-1alpha (HIF-1alpha) is a master regulator in the cellular response to hypoxic conditions, and rheumatoid synovial tissue is known to exist under hypoxic conditions. Therefore, this study was conducted to determine the contribution of HIF-1alpha to hypoxia-induced MMP and cytokine production in fibroblast-like synoviocytes (FLS). METHODS RA FLS were transfec...

INTRODUCTION Interleukin-34 (IL-34) is a recently defined cytokine, showing a functional overlap with macrophage colony stimulating factor (M-CSF). This study was undertaken to address the expression of IL-34 in rheumatoid arthritis (RA) patients and to investigate its regulation and pathogenic role in RA. METHODS IL-34 levels were determined in the RA synovium, synovial fluid (SF) and fibrob...

The application of fuzzy logic (FL) supervisors (FLS) for on-line nonlinear auto-tuning of the basic FL controllers (FLCs) gains popularity as a simple adaptive technique for improvement of the performance of control systems for plants with nonlinearities, inertia, time-delay, model uncertainty and variable parameters. Various approaches for the FLS design are developed for different types of F...

The production of IgG rheumatoid factors in the inflamed synovium of many patients with rheumatoid arthritis (RA) implies that local sites exist where plasma cell precursors undergo isotype switching and affinity maturation by somatic mutation and selection. Lymphonodular infiltrates of the synovium-containing germinal centers (GCs), are candidates to fulfill such function in the rheumatoid pat...

A new learning methodology based on a hybrid algorithm for interval type-2 fuzzy logic systems (FLS) parameter estimation is presented. The new proposal consists of Back-Propagation with Recursive Least-Squares (BP-RLS) and BackPropagation with square-root filter (BP-REFIL). A system with the proposed methodology was simulated to test its capability for output surface temperature prediction of ...

Recent studies of the pathogenesis of rheumatoid arthritis (RA) have revealed that both synovial fibroblasts and T cells participate in the perpetuation of joint inflammation as dynamic partners in a mutual activation feedback, via secretion of cytokines and chemokines that stimulate each other. In this study, we investigated the role of IL-17, a major Th1 cytokine produced by activated T cells...