Landscape organized (or structured) heterogeneity influences hydrological and biogeochemical patterns across space time. We developed landscape indices that describe the spatial configuration of nutrient sources sinks as a function their distance to stream (lateral dimension) or outlet (longitudinal intersection with flow-accumulation areas. Using monthly nitrate, total phosphorus (TP), soluble...

To investigate the role of cell viability and metabolism on the myocardial kinetics of a new tracer, technetium-99m-methoxyisobutyl isonitrile (Tc-99m-MIBI), 250 ,uCi/l Tc-99m-MIBI was infused in isolated rat hearts under constant flow conditions. The hearts were studied after inducing irreversible damage by cytochrome c oxidase inhibitor sodium cyanide (n=8) or sarcolemmal membrane detergent T...

The morphology and kinetics of pinocytosis by bone marrow-derived macrophages were studied to determine how stimulation by phorbol esters increases net solute accumulation. Application of phorbol myristate acetate (PMA) increased both the abundance of macropinosomes and the rate of solute flow through the endocytic compartment. The large pinosomes originated as ruffles at the cell margins that ...

The aim of the study was to investigate the role of endogenous sulfur dioxide (SO2)/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO2/AAT1 pathway and increased collagen I and III protein expression. Importantly, AAT1 overexpression blocked the increase in collagen I and III expression, trans...

0019-1035/$ see front matter 2011 Elsevier Inc. A doi:10.1016/j.icarus.2011.07.018 ⇑ Corresponding author. E-mail addresses: [email protected] (J.L. Fasto (J.W. Head). A fretted valley system on Mars located at the northern mid-latitude dichotomy boundary contains lineated valley fill (LVF) with extensive flow-like features interpreted to be glacial in origin. We have modeled this deposit using...

BACKGROUND The aim of this study was to clarify the mechanism of accumulation of 5-aminolevulinic acid (ALA)-dependent protoporphyrin IX (PpIX), ALA-photodynamic therapy (PDT)-induced cell death and enhanced efficiency by a ferrochelatase inhibitor in prostate cancer PC-3 cells. METHODS The accumulation of ALA-induced PpIX in PC-3 cells was observed by fluorescence microscopy and measured by ...

BACKGROUND Nasal nitric oxide is present in high concentrations in the upper airway relative to the lower respiratory tract. OBJECTIVE To explore the rate of nitric oxide accumulation in the nonventilated nasal cavity. METHODS In 9 healthy subjects previously trained to close the soft palate, steady-state plateau nitric oxide levels were recorded while air was aspirated through the nasal ai...

Seven anesthetized dogs treated with prostaglandin I2, indomethacin, and heparin were compared with 12 controls to test the hypothesis that the salutary effect of treatment on recovery of neuronal function and cerebral blood flow (CBF) after ischemia is coupled to the inhibition of platelet accumulation. In this model of right hemisphere multifocal ischemia, cortical somatosensory evoked respon...

The surface of insulators accumulates charge during subject to high voltage stresses electrically.The surface charging causes deteriorations of electrical performance and durability of high voltage insulators in gas. In this paper, we describe a result of visual analysis of electric fields with accumulation charge on complex insulator surface to clear the effect of surface charging on the diele...

As one of the important tasks in digital terrain analysis, the calculation of flow accumulations from gridded digital elevation models (DEMs) usually involves two steps in a real application: (1) using an iterative DEM preprocessing algorithm to remove the depressions and flat areas commonly contained in real DEMs, and (2) using a recursive flow-direction algorithm to calculate the flow accumul...